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Stephen R. Thom
Researcher at University of Maryland, Baltimore
Publications - 159
Citations - 11603
Stephen R. Thom is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Nitric oxide & Carbon monoxide poisoning. The author has an hindex of 54, co-authored 154 publications receiving 10473 citations. Previous affiliations of Stephen R. Thom include University of Pennsylvania & Children's Hospital of Philadelphia.
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Journal ArticleDOI
Carbon monoxide poisoning--a public health perspective.
TL;DR: In conclusion, CO poisoning occurs frequently; has severe consequences, including immediate death; involves complications and late sequelae; and often is overlooked.
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Diabetic impairments in NO-mediated endothelial progenitor cell mobilization and homing are reversed by hyperoxia and SDF-1α
Katherine A. Gallagher,Zhao-Jun Liu,Min Xiao,Haiying Chen,Lee J. Goldstein,Donald G. Buerk,April Nedeau,Stephen R. Thom,Omaida C. Velazquez +8 more
TL;DR: Administration of SDF-1alpha into wounds reversed the EPC homing impairment and, with hyperoxia, synergistically enhanced EPC mobilization, homing, and wound healing, which can significantly advance the field of diabetic wound healing.
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Correlation between intraluminal oxygen gradient and radial partitioning of intestinal microbiota.
Lindsey Albenberg,Tatiana V. Esipova,Colleen Judge,Kyle Bittinger,Jun Chen,Alice Laughlin,Stephanie Grunberg,Robert N. Baldassano,James D. Lewis,Hongzhe Li,Stephen R. Thom,Frederic D. Bushman,Sergei A. Vinogradov,Gary D. Wu +13 more
TL;DR: A radial gradient of microbes linked to the distribution of oxygen and nutrients provided by host tissue is observed in an analysis of intestinal microbiota of mice and human beings.
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Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo
Ara A. Vaporciyan,Horace M. DeLisser,Horng Chin Yan,I. Mendiguren,Stephen R. Thom,Michael L. Jones,Peter A. Ward,Steven M. Albelda +7 more
TL;DR: It appears that PECAM-1 is required for neutrophil transmigration in vivo and may thus be a potential therapeutic target.
Journal ArticleDOI
Hyperbaric oxygen – its mechanisms and efficacy
TL;DR: Clinical and mechanistic data support use of hyperbaric oxygen for a variety of disorders, but further work is needed to clarify clinical utility for some disorders and to hone patient selection criteria to improve cost efficacy.