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Alice Laughlin

Researcher at University of Pennsylvania

Publications -  10
Citations -  1650

Alice Laughlin is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Gut flora & Deep sequencing. The author has an hindex of 8, co-authored 10 publications receiving 1323 citations.

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Comparison of placenta samples with contamination controls does not provide evidence for a distinct placenta microbiota.

TL;DR: This sample set could not distinguish between placental samples and contamination introduced during DNA purification, and no placental bacterial lineages were shared between extraction methods, though oral and vaginal samples showed characteristic, distinctive composition.
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Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation

TL;DR: Data indicate that helminth-induced immunomodulation occurs independently of changes in the microbiota but is dependent on Ym1, a chitinase-like molecule that is associated with alternatively activated macrophages, which could partially restore antiviral immunity.
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Composition and dynamics of the respiratory tract microbiome in intubated patients

TL;DR: Longitudinal analysis of respiratory tract microbiota in critically ill patients provides insight into the pathogenesis and diagnosis of LRTI and holds promise for expanded pathogen identification.
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Improved characterization of medically relevant fungi in the human respiratory tract using next-generation sequencing

TL;DR: Using an improved method for contamination filtering, it is possible to characterize fungal communities in the human respiratory tract more accurately and explore their interactions with bacterial communities in health and disease.