Stephen R. Thomas

TL;DR: The MIRD Committee objectives are to restate its schema for assessment of absorbed dose in a manner consistent with the needs of both the nuclear medicine and the radiation protection communities, and to formally adopt the dosimetry quantities equivalent dose and effective dose for use in comparative evaluations of potential risks of radiation-induced stochastic effects to patients after nuclear medicine procedures.

TL;DR: This report describes recommended techniques for radiopharmaceutical biodistribution data acquisition and analysis in human subjects to estimate radiation absorbed dose using the Medical Internal Radiation Dose (MIRD) schema.

TL;DR: Evaluated responses to therapeutic irradiation with 131I in 76 patients with thyroid adenocarcinoma found patients with metastases that persisted after 131I therapy tended to have more advanced disease and received significantly lower radiation doses per millicurie of administered 131I than did persons whose lesions responded to treatment.

TL;DR: Success rates are equal to or better than those reported with empiric methods of 131I administration and the individualized treatment planning selectively allocates hospitalization and higher exposures to 131I to those patients who require them.

TL;DR: Indication of an influence of the residence time of radioiodine in the blood on the fractional uptake into thyroid remnant was found and a novel regimen is proposed in which therapeutic activities to be administered are determined from the individual specific blood dose.