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Stephen T. Lee

Researcher at United States Department of Agriculture

Publications -  131
Citations -  2016

Stephen T. Lee is an academic researcher from United States Department of Agriculture. The author has contributed to research in topics: Sudden death & Tremetone. The author has an hindex of 22, co-authored 130 publications receiving 1686 citations. Previous affiliations of Stephen T. Lee include Agricultural Research Service.

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Development of enzyme-linked immunosorbent assays for the hepatotoxic alkaloids riddelliine and riddelliine N-oxide.

TL;DR: Two competitive inhibition enzyme-linked immunosorbent assays for riddelliine, riddellii N-oxide, and other closely related pyrrolizidine alkaloids were developed using polyclonal antibodies and suggest that these techniques will be excellent tools to diagnose poisoned animals and identify highly toxic plants.
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Quantitative method for the measurement of three benzofuran ketones in rayless goldenrod (Isocoma pluriflora) and white snakeroot (Ageratina altissima) by high-performance liquid chromatography (HPLC).

TL;DR: Differences in concentrations of tremetone, dehydrot Remetone, and 3-oxyangeloyl-tremetone in white snakeroot and rayless goldenrod plants may explain the historical sporadic and unpredictable toxicity of these plants to livestock and humans.
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Identification of Indole Diterpenes in Ipomoea asarifolia and Ipomoea muelleri, Plants Tremorgenic to Livestock

TL;DR: This is the first detailed MS analysis of known indole diterpenes and possible isomers in I. asarifolia and I. muelleri and provides valuable information for indoles diterpene characterization.
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A swainsonine survey of North American Astragalus and Oxytropis taxa implicated as locoweeds.

TL;DR: Forty of the fifty-three swainsonine-positive taxa had not been determined to contain swains onine previously using liquid or gas chromatography coupled with mass spectrometry and will serve as a reference for risk assessment and diagnostic purposes.
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Phytochemicals: The Good, the Bad and the Ugly?

TL;DR: In this paper, the authors present examples of plants poisonous to animals and include the steroidal alkaloid toxin of Veratrum californicum (Western false hellebore), piperidine alkaloids of Lupinus species (lupines), and polyhydroxy indolizidine, pyrrolizidine and nortropane alkalids of Astragalus and Oxytropis species (locoweeds), Castanospermum australe (Moreton Bay chestnut) and Ipomoea species (morning glories).