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Stephen T. Lee

Researcher at United States Department of Agriculture

Publications -  131
Citations -  2016

Stephen T. Lee is an academic researcher from United States Department of Agriculture. The author has contributed to research in topics: Sudden death & Tremetone. The author has an hindex of 22, co-authored 130 publications receiving 1686 citations. Previous affiliations of Stephen T. Lee include Agricultural Research Service.

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Tremorgenic Indole Diterpenes from Ipomoea asarifolia and Ipomoea muelleri and the Identification of 6,7-Dehydro-11-hydroxy-12,13-epoxyterpendole A

TL;DR: To better characterize the tremorgenic activity of the major indole diterpene alkaloids in these two plants, terpendole K, 6,7-dehydroterpendole A, 11-hydroxy-12,13-epoxyterpendoles K, paxilline, and a new compound were isolated and evaluated in a mouse model.
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Cattle Consumption of Velvet Lupine (Lupinus leucophyllus) in the Channel Scablands of Eastern Washington

TL;DR: Lupine consumption occurred during the critical period of gestation in 2 of the 3 years, but no crooked calves were produced, apparently, the cows did not ingest sufficient amounts of anagyrine over the susceptible period of time to produce crooked calves.
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Piperidine, pyridine alkaloid inhibition of fetal movement in a day 40 pregnant goat model.

TL;DR: The blockade of anabasine and myosmine actions in TE-671 cells by alpha conotoxin GI indicates that they are agonists at fetal muscle-type nAChR, suggesting a potential for these alkaloids to cause multiple congenital contracture-type defects in developing fetuses.
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A toxicokinetic comparison of two species of low larkspur (Delphinium spp.) in cattle

TL;DR: The results suggest the elimination rates of norditerpene alkaloids from different larkspur species in cattle are similar regardless of plant alkaloid composition.
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Stereoselective Potencies and Relative Toxicities of γ-Coniceine and N-Methylconiine Enantiomers

TL;DR: The results from this study suggest γ-coniceine is a more potent agonist than the enantiomers of N-methylconiine and that there is a stereoselective difference in the in vitro potencies of the en Anti-N- methylconiine that correlates with the relative toxicities of theEnantiomers in vivo.