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Steve Goodison
Researcher at Mayo Clinic
Publications - 95
Citations - 3394
Steve Goodison is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Bladder cancer & Cancer. The author has an hindex of 32, co-authored 88 publications receiving 2925 citations. Previous affiliations of Steve Goodison include Orlando Regional Medical Center & Orlando Health.
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Local-Learning-Based Feature Selection for High-Dimensional Data Analysis
TL;DR: This paper considers feature selection for data classification in the presence of a huge number of irrelevant features, and proposes a new feature-selection algorithm that addresses several major issues with prior work, including problems with algorithm implementation, computational complexity, and solution accuracy.
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Bladder Cancer Detection and Monitoring: Assessment of Urine- and Blood-Based Marker Tests
TL;DR: The performance of current diagnostic assays for bladder cancer is assessed and some of the emerging biomarkers that could be developed to augment current bladder cancer detection strategies are discussed.
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Role of telomerase in cell senescence and oncogenesis
TL;DR: The role of telomeres and telomerase in senescence and tumor progression is reviewed, and the potential use of telomerases in diagnosis and treatment is discussed.
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Expression of CXCL1 in human endothelial cells induces angiogenesis through the CXCR2 receptor and the ERK1/2 and EGF pathways.
TL;DR: Data is presented on the role of CXCL1 in human endothelial cells inducing angiogenesis and on the interactions between the endothelial and epithelial components, which will provide insight into how human tissues use CxCL1 to survive and thrive in a hostile environment.
Journal Article
Progressive loss of CD44 gene expression in invasive bladder cancer.
Takashi Sugino,Hazel Gorham,Kazuhiro Yoshida,John Bolodeoku,Vinod Nargund,David Cranston,Steve Goodison,David Tarin +7 more
TL;DR: The results indicate that initially there is a striking increase in CD44 gene expression in early bladder carcinomas, relative to normal urothelium, but that this diminishes as the tumors acquire a more aggressive phenotype.