S
Stuart A. Newman
Researcher at New York Medical College
Publications - 198
Citations - 8470
Stuart A. Newman is an academic researcher from New York Medical College. The author has contributed to research in topics: Limb bud & Multicellular organism. The author has an hindex of 51, co-authored 194 publications receiving 7889 citations. Previous affiliations of Stuart A. Newman include Wellcome Trust Sanger Institute & Memorial Sloan Kettering Cancer Center.
Papers
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Journal ArticleDOI
Epigenetic Mechanisms of Character Origination
TL;DR: This work proposes that the present relationship between genes and form is a highly derived condition, a product of evolution rather than its precondition, and helps to explain findings that are difficult to reconcile with the standard neo-Darwinian model.
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Mechanisms of pattern formation in development and evolution
TL;DR: It is suggested that differences in `variational properties' lead to morphostatic and morphodynamic mechanisms being represented to different extents in early and late stages of development and to their contributing in distinct ways to morphological transitions in evolution.
Journal ArticleDOI
Dynamics of skeletal pattern formation in developing chick limb
Stuart A. Newman,Harry L. Frisch +1 more
TL;DR: During development of the embryonic chick limb the skeletal pattern is laid out as cartilaginous primordia, which emerge in a proximodistal sequence over a period of 4 days, leading to sequential reorganizations of the morphogen pattern.
Book
Biological Physics of the Developing Embryo
Gabor Forgacs,Stuart A. Newman +1 more
TL;DR: The cell is fundamental unit of developmental systems as mentioned in this paper, and cell states include stability, oscillation, differentiation, adhesion, compartmentalization and lumen formation, and pattern formation: segmentation, axes and asymmetry.
Journal ArticleDOI
Cell elongation is key to in silico replication of in vitro vasculogenesis and subsequent remodeling.
Roeland M. H. Merks,Sergey V. Brodsky,Michael S. Goligorksy,Stuart A. Newman,James A. Glazier +4 more
TL;DR: Using a cell-centered computational model, it is shown that the endothelial cells' elongated shape is key to correct spatiotemporal in silico replication of stable vascular network growth.