S
Stuart A. Newman
Researcher at New York Medical College
Publications - 198
Citations - 8470
Stuart A. Newman is an academic researcher from New York Medical College. The author has contributed to research in topics: Limb bud & Multicellular organism. The author has an hindex of 51, co-authored 194 publications receiving 7889 citations. Previous affiliations of Stuart A. Newman include Wellcome Trust Sanger Institute & Memorial Sloan Kettering Cancer Center.
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Journal ArticleDOI
Continuous macroscopic limit of a discrete stochastic model for interaction of living cells.
TL;DR: A general multiscale approach is demonstrated by simulating spongy bone formation, suggesting that self-organizing physical mechanisms can account for this developmental process.
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Borrelia burgdorferi Binds to, Invades, and Colonizes Native Type I Collagen Lattices
Maria C. Zambrano,Anastasia A. Beklemisheva,Anton V. Bryksin,Stuart A. Newman,Felipe C. Cabello +4 more
TL;DR: The high efficiency of binding of B. burgdorferi strains to intact collagen matrices permits replacement of the commonly used isotopic binding assay with visual fluorescent microscopic assays and will facilitate future studies of these interactions.
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Application of Discontinuous Galerkin Methods for Reaction-Diffusion Systems in Developmental Biology
TL;DR: Numerical solutions of two reaction-diffusion systems, the well-studied Schnakenberg model, and a new biologically based system for skeletal pattern formation in the vertebrate limb are presented to demonstrate effects of various domain geometries on the resulting biological patterns.
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Problems and paradigms: Is segmentation generic?
TL;DR: It is suggested that the complex, multicom-ponent segment-forming systems found in contemporary organisms are the products of evolutionary recruitment of molecular cues that increase the reliability and stability of metameric patterns originally templated by generic self-organizing properties of tissues.
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A regulatory network of two galectins mediates the earliest steps of avian limb skeletal morphogenesis
TL;DR: It is indicated that CG-1A and CG-8 constitute a multiscale network that is a major mediator, earlier-acting than any previously described, of the formation and patterning of precartilage mesenchymal condensations in the developing limb.