S
Stuart A. Newman
Researcher at New York Medical College
Publications - 198
Citations - 8470
Stuart A. Newman is an academic researcher from New York Medical College. The author has contributed to research in topics: Limb bud & Multicellular organism. The author has an hindex of 51, co-authored 194 publications receiving 7889 citations. Previous affiliations of Stuart A. Newman include Wellcome Trust Sanger Institute & Memorial Sloan Kettering Cancer Center.
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Book ChapterDOI
Phase transitions, interfaces, and morphogenesis in a network of protein fibers.
Gabor Forgacs,Stuart A. Newman +1 more
TL;DR: This chapter presents results obtained in a model tissue system based, in part, on materials from the extracellular matrix of mesenchymal tissues and may provide a model for shape change in such tissues.
Book ChapterDOI
Multi-model simulations of chicken limb morphogenesis
Rajiv Chaturvedi,Jesús A. Izaguirre,Chengbang Huang,Trevor Cickovski,Patrick Michael Virtue,Gilberto L. Thomas,Gabor Forgacs,Mark Alber,G. Hentschel,Stuart A. Newman,James A. Glazier +10 more
TL;DR: COMPUCELL, a multi-model software framework for simulations of morphogenesis, simulates the formation of the skeletal pattern in the avian limb bud, which requires simulations based on interactions of the genetic regulatory network with generic cellular mechanisms.
Journal ArticleDOI
Sleeper cells: The stringent response and persistence in the Borreliella (Borrelia) burgdorferi enzootic cycle
TL;DR: B. burgdorferi may constitute a linchpin in multiple aspects of infections with Lyme disease borrelia, providing a link between the micro-ecological challenges of its enzootic life-cycle and long-term residence in the tissues of its animal reservoirs, with the evolutionary side effect of potential persistence in incidental human hosts.
Book ChapterDOI
A hybrid discrete-continuum model for 3-D skeletogenesis of the vertebrate limb
Rajiv Chaturvedi,Chengbang Huang,Jesús A. Izaguirre,Stuart A. Newman,James A. Glazier,Mark Alber +5 more
TL;DR: The integrated model combines submodels that address length-scales from subcellular to tissues and organs in a unified framework and applies the model spatiotemporal bone patterning in the proximo-distal direction of developing avian limb.
Journal ArticleDOI
The vertebrate limb: An evolving complex of self-organizing systems.
TL;DR: A unified interpretation of the evolution and functioning of these skeletogenic networks over evolution is presented in the context of an independently evolved system of Hox protein and Shh gradients that interfaced with them to tune the spatial wavelengths and refine the identities of the resulting arrays of elements.