S
Stuart C. Clarke
Researcher at University of Southampton
Publications - 178
Citations - 5816
Stuart C. Clarke is an academic researcher from University of Southampton. The author has contributed to research in topics: Pneumococcal conjugate vaccine & Streptococcus pneumoniae. The author has an hindex of 38, co-authored 169 publications receiving 4978 citations. Previous affiliations of Stuart C. Clarke include Stobhill Hospital & University of Glasgow.
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Journal ArticleDOI
Impact of meningococcal serogroup C conjugate vaccines on carriage and herd immunity
Martin C. J. Maiden,Ana Belén Ibarz-Pavón,Rachel Urwin,Stephen J. Gray,Nick Andrews,Stuart C. Clarke,A. Mark Walker,Meirion Rhys Evans,J. Simon Kroll,Keith R. Neal,Dlawer A. A. Ala'Aldeen,Derrick W. Crook,Kathryn Cann,Sarah Harrison,R. Cunningham,David Baxter,Edward B. Kaczmarski,Jenny M. MacLennan,J. Claire Cameron,James M. Stuart +19 more
TL;DR: The impact of vaccination with MCC vaccine on the prevalence of carriage of group C meningococci was consistent with herd immunity, and the high impact on the carriage of ST-11 complex serogroup C could be attributed to high levels of capsule expression.
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Secondary Bacterial Infections Associated with Influenza Pandemics.
TL;DR: With increased antibiotic resistance and vaccine evasion it is important to monitor the epidemiology of pathogens in circulation to inform clinical treatment and development, particularly in the setting of an influenza epidemic/pandemic.
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Virulence of Enteropathogenic Escherichia coli, a Global Pathogen
TL;DR: This review aims to provide a broad overview of and update to the virulence aspects of EPEC, which provides a good virulence model of other E. coli infections as well as other pathogenic bacteria.
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Longitudinal profiling of the lung microbiome in the AERIS study demonstrates repeatability of bacterial and eosinophilic COPD exacerbations
David L. Mayhew,Nathalie Devos,Christophe Lambert,James R. Brown,Stuart C. Clarke,Viktoriya Kim,Michal Magid-Slav,Bruce E. Miller,Kristoffer Ostridge,Ruchi Patel,Ganesh M. Sathe,Daniel F Simola,Karl J. Staples,Ruby Sung,Ruth Tal-Singer,Andrew Tuck,Stephanie Van Horn,Vincent Weynants,Nicholas P. Williams,Jeanne-Marie Devaster,Tom Wilkinson +20 more
TL;DR: In insights pertaining to the identification of bacterial targets in the lung and biomarkers to classify COPD subtypes and to determine appropriate treatments for the patient, the stability of the lung microbiome over time was more likely to be decreased in exacerbations and within individuals with higher exacerbation frequencies.
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Diarrhoeagenic Escherichia coli—an emerging problem?
TL;DR: Diarrhea remains one of the main sources of morbidity and morbidity in today's world and a large proportion is caused by diarrheagenic Escherichia coli, a large and emerging problem without the availability of effective vaccines.