S
Stylianos E. Antonarakis
Researcher at University of Geneva
Publications - 758
Citations - 99393
Stylianos E. Antonarakis is an academic researcher from University of Geneva. The author has contributed to research in topics: Gene & Chromosome 21. The author has an hindex of 138, co-authored 746 publications receiving 93605 citations. Previous affiliations of Stylianos E. Antonarakis include Northwestern University & Gujarat University.
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Journal ArticleDOI
Gene age predicts the strength of purifying selection acting on gene expression variation in humans.
Konstantin Popadin,Konstantin Popadin,Maria Gutierrez-Arcelus,Maria Gutierrez-Arcelus,Tuuli Lappalainen,Alfonso Buil,Alfonso Buil,Julia Steinberg,Julia Steinberg,Sergey Nikolaev,Samuel W. Lukowski,Georgii A. Bazykin,Georgii A. Bazykin,Vladimir B. Seplyarskiy,Vladimir B. Seplyarskiy,Panagiotis Ioannidis,Panagiotis Ioannidis,Evgeny M. Zdobnov,Evgeny M. Zdobnov,Emmanouil T. Dermitzakis,Stylianos E. Antonarakis +20 more
TL;DR: It is demonstrated that gene connectivity, gene involvement in complex regulatory networks, gene haploinsufficiency, and the strength of posttranscriptional regulation increase with gene age, implying a reduction of the environmental component.
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Carrier testing strategy in haemophilia a
Robert L. Janco,John A. Phillips,Pamela J Orlando,Kay E. Davies,John M. Old,Stylianos E. Antonarakis +5 more
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Yeast artificial chromosome vectors for efficient clone manipulation and mapping
TL;DR: YACs generated using this vector system contain a yeast gene (SUP 11) that allows visual monitoring of YAC stability and copy number, and the vectors contain a polylinker with unique EcoRI, BglII, NotI, EagI, SacII, SalI, Nrui, NheI, and ClaI cloning sites.
Journal Article
Molecular genetics of hemophilia A in man (factor VIII deficiency).
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Localization of 102 exons to a 2.5 Mb region involved in Down syndrome
Diane Lucente,Haiming Chen,D.K. Shea,Sonia Samec,M. Rutter,Roman Chrast,Colette Rossier,Alan Buckler,Stylianos E. Antonarakis,Mary Kay McCormick +9 more
TL;DR: An integrated physical and transcript map will be valuable for fine mapping of DNA from individuals with partial aneuploidy of chromosome 21 as well as for assessing and ultimately generating a complete gene map of this segment of the genome.