S
Su-Li Cheng
Researcher at Washington University in St. Louis
Publications - 35
Citations - 3712
Su-Li Cheng is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Osteoblast & Cellular differentiation. The author has an hindex of 26, co-authored 35 publications receiving 3650 citations. Previous affiliations of Su-Li Cheng include Vanderbilt University & University of Washington.
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Differentiation of human bone marrow osteogenic stromal cells in vitro: induction of the osteoblast phenotype by dexamethasone
TL;DR: The results, which demonstrate that Dex conditions the differentiation of human bone marrow osteogenic stromal cells into osteoblast-like cells, support the hypothesis of a permissive effect of glucocorticoids in ensuring an adequate supply of mature osteOBlast populations.
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Erk Is Essential for Growth, Differentiation, Integrin Expression, and Cell Function in Human Osteoblastic Cells
Chung-Fang Lai,Lala R. Chaudhary,Aurora Fausto,Linda R. Halstead,Daniel S. Ory,Louis V. Avioli,Su-Li Cheng +6 more
TL;DR: The data suggest that Erks are not only essential for the growth and differentiation of osteoblasts but also are important for osteoblast adhesion, spreading, migration, and integrin expression.
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Regulation of bone matrix protein expression and induction of differentiation of human osteoblasts and human bone marrow stromal cells by bone morphogenetic protein‐2
TL;DR: BMP‐2 has profound effects on the proliferation, expression of most of the bone matrix proteins and the mineralization of both relatively immature human bone marrow stromal preosteoblasts and mature human osteoblasts.
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Signal Transductions Induced by Bone Morphogenetic Protein-2 and Transforming Growth Factor-β in Normal Human Osteoblastic Cells
Chung-Fang Lai,Su-Li Cheng +1 more
TL;DR: To determine the roles of MAPK in BMP-2 and TGF-β function, the effect of ERK and p38 inhibitors on the regulation of bone matrix protein expression and JunB and JunD levels by these two factors was analyzed.
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Induction of Bone Formation Using a Recombinant Adenoviral Vector Carrying the Human BMP-2 Gene in a Rabbit Spinal Fusion Model
TL;DR: The feasibility of employing gene therapy using recombinant adenoviral vectors as a tool for enhancing spine fusion is suggested and the transduction results in transformation of these cells into an osteoprogenitor line capable of producing bone in vivo.