Sudarshan Kini

TL;DR: CXI-benzo-84 inhibited cell cycle progression in metaphase stage of mitosis and accumulated spindle assembly checkpoint proteins Mad2 and BubR1 on kinetochores, which subsequently activated apoptotic cell death in cancer cells.

TL;DR: Focusing on these criteria, the diversification of polymeric scaffolds based on their available resources is discussed in detail, the well‐founded and latest techniques of scaffold fabrication, and their applications pertaining to tissue engineering, drug screening, and tumor model development.

TL;DR: This chapter describes the recent studies on algae and cyanobacteria as a promising source of novel compounds with a particular focus on novel extraction techniques, bioactivity, clinical research, and biomedical applications.

TL;DR: The preparation of LbL-nanoSraf comprising of layer-by-layer (LbL) assembled polyelectrolytes dextran-sulfate/poly-l-arginine, with a multikinase inhibitor sorafenib encapsulated calcium carbonate (CaCO3) nanoparticles for oral cancer therapy in vitro exhibited more potent antiproliferative, apoptotic and antimigratory activities in KB cells than the free drug Sraf.

TL;DR: In this paper, a simple, facile, and cost-effective one pot synthesis route to synthesize MPA (3-mercaptopropionic acid) stabilized CdTe/CdS core-shell quantum dots and its application for detection of mercury using the fluorescence resonance energy transfer with a cationic dye, Rhodamine 6G.