S
Suman Ghosal
Researcher at Indian Association for the Cultivation of Science
Publications - 20
Citations - 1220
Suman Ghosal is an academic researcher from Indian Association for the Cultivation of Science. The author has contributed to research in topics: microRNA & Regulation of gene expression. The author has an hindex of 11, co-authored 19 publications receiving 992 citations. Previous affiliations of Suman Ghosal include National Institutes of Health & Indian Institute of Engineering Science and Technology, Shibpur.
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Circ2Traits: a comprehensive database for circular RNA potentially associated with disease and traits.
TL;DR: The interactions of circRNAs with disease associated miRNAs were identified, following which the likelihood of a circRNA being associated with a disease was calculated and a database of disease-circRNA association in Circ2Traits, the first comprehensive knowledgebase of potential association of circular RNAs with diseases in human.
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Competing Endogenous RNA: The Key to Posttranscriptional Regulation
TL;DR: This brief review focuses on the molecular mechanism of ceRNA as part of the complex post-transcriptional regulatory circuit in cell and the impact of ceRNAs in development and disease.
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lnCeDB: database of human long noncoding RNA acting as competing endogenous RNA.
TL;DR: In this article, the likelihood of an lncRNA-mRNA pair for actually being ceRNA was estimated by using hypergeometric test using the ratio of the number of shared MREs between the pair with the total number of mREs of the individual candidate gene.
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The Human CCHC-type Zinc Finger Nucleic Acid-Binding Protein Binds G-Rich Elements in Target mRNA Coding Sequences and Promotes Translation
Daniel Benhalevy,Sanjay K. Gupta,Charles H. Danan,Suman Ghosal,Hong-Wei Sun,Hinke G. Kazemier,Katrin Paeschke,Markus Hafner,Stefan Juranek,Stefan Juranek +9 more
TL;DR: Functional analyses revealed that CNBP binding did not influence target mRNA abundance but rather increased their translational efficiency, and it is hypothesize that CN BP is supporting translation by resolving stable structures on mRNAs.
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Long Noncoding RNAs: New Players in the Molecular Mechanism for Maintenance and Differentiation of Pluripotent Stem Cells
TL;DR: This review focuses on recent findings on the regulatory role of lncRNAs in two main aspects of pluripotency, namely, self renewal and differentiation into any lineage, and elucidates the underlying molecular mechanisms that are being uncovered lately.