S
Suman Rijal
Researcher at B.P. Koirala Institute of Health Sciences
Publications - 153
Citations - 8554
Suman Rijal is an academic researcher from B.P. Koirala Institute of Health Sciences. The author has contributed to research in topics: Visceral leishmaniasis & Leishmaniasis. The author has an hindex of 50, co-authored 149 publications receiving 7911 citations.
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Journal ArticleDOI
Visceral leishmaniasis: what are the needs for diagnosis, treatment and control?
François Chappuis,François Chappuis,Shyam Sundar,Asrat Hailu,H. W. Ghalib,Suman Rijal,Rosanna W. Peeling,Jorge Alvar,Marleen Boelaert +8 more
TL;DR: Millefosine, paromomycin and liposomal amphotericin B are gradually replacing pentavalent antimonials and conventional amphoteric in B as the preferred treatments in some regions, but in other areas these drugs are still being evaluated in both mono- and combination therapies.
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Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance
Tim Downing,Hideo Imamura,Saskia Decuypere,Taane G. Clark,Graham H. Coombs,James Cotton,James D. Hilley,Simonne De Doncker,Ilse Maes,Jeremy C. Mottram,Michael A. Quail,Suman Rijal,Mandy Sanders,Gabriele Schönian,Olivia Stark,Shyam Sundar,Manu Vanaerschot,Christiane Hertz-Fowler,Jean-Claude Dujardin,Matthew Berriman +19 more
TL;DR: It is shown that whole-genome sequence data reveals genetic structure within these lines not shown by multilocus typing, and suggests that drug resistance has emerged multiple times in this closely related set of lines, providing additional power to track the drug resistance and epidemiology of an important human pathogen.
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A meta-analysis of the diagnostic performance of the direct agglutination test and rK39 dipstick for visceral leishmaniasis
TL;DR: The diagnostic performance of the direct agglutination test and the rK39 dipstick for visceral leishmaniasis is good to excellent and seem comparable.
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Increasing Failure of Miltefosine in the Treatment of Kala-azar in Nepal and the Potential Role of Parasite Drug Resistance, Reinfection, or Noncompliance
Suman Rijal,Bart Ostyn,Surendra Uranw,Surendra Uranw,Keshav Rai,Narayan Raj Bhattarai,Thomas P. C. Dorlo,Thomas P. C. Dorlo,Jos H. Beijnen,Manu Vanaerschot,Saskia Decuypere,S. S. Dhakal,Murari Lal Das,Prahlad Karki,Rupa Singh,Marleen Boelaert,Jean-Claude Dujardin,Jean-Claude Dujardin +17 more
TL;DR: Relapse in one-fifth of the MIL-treated patients observed in this study is an alarming signal for the VL elimination campaign, urging for further review and cohort monitoring.
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Diagnostic tests for kala-azar: a multi-centre study of the freeze-dried DAT, rK39 strip test and KAtex in East Africa and the Indian subcontinent.
Marleen Boelaert,Sayda El-Safi,Asrat Hailu,Moawia M. Mukhtar,Suman Rijal,Shyam Sundar,Monique Wasunna,Abraham Aseffa,Jane Mbui,Joris Menten,Philippe Desjeux,Rosanna W. Peeling +11 more
TL;DR: Three diagnostic tests for visceral leishmaniasis (VL), the freeze-dried direct agglutination test (FD-DAT), the rK39 dipstick and a urine latex antigen test (KAtex), were evaluated for use in primary care in East Africa and the Indian subcontinent.