S
Sumi Elsa John
Publications - 32
Citations - 474
Sumi Elsa John is an academic researcher. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 11, co-authored 25 publications receiving 324 citations.
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Journal ArticleDOI
Genetic Substructure of Kuwaiti Population Reveals Migration History
Osama Alsmadi,Gaurav Thareja,Fadi Alkayal,Ramakrishnan Rajagopalan,Sumi Elsa John,Prashantha Hebbar,Kazem Behbehani,Thangavel Alphonse Thanaraj +7 more
TL;DR: Identity by Descent and Homozygosity analyses find Kuwait’s population to be heterogeneous with Kuwait S as highly endogamous, and Kuwait B as diverse, while results of analysis for genetic features such as linkage disequilibrium decay patterns conform to Kuwait's geographical location at the nexus of Africa, Europe, and Asia.
Journal ArticleDOI
SARS-CoV-2: Possible recombination and emergence of potentially more virulent strains.
Dania Haddad,Sumi Elsa John,Anwar Mohammad,Maha M. Hammad,Prashantha Hebbar,Arshad Channanath,Rasheeba Nizam,Sarah Al-Qabandi,Ashraf Al Madhoun,Abdullah Alshukry,Hamad Ali,Thangavel Alphonse Thanaraj,Fahd Al-Mulla +12 more
TL;DR: In this article, the authors proposed that genomic recombination between different strains may contribute to SARS-CoV-2 virulence and COVID-19 severity and may present additional challenges for current treatment regimens and countermeasures.
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Genome at juncture of early human migration: a systematic analysis of two whole genomes and thirteen exomes from Kuwaiti population subgroup of inferred Saudi Arabian tribe ancestry.
Osama Alsmadi,Sumi Elsa John,Gaurav Thareja,Prashantha Hebbar,Dinu Antony,Kazem Behbehani,Thangavel Alphonse Thanaraj +6 more
TL;DR: The first genome resource imperative for designing future genetic studies in Saudi Arabian tribe subgroup is presented and a set of 2,485 SNPs show significantly different allele frequencies when compared to populations from other continents.
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Prognostic Genetic Markers for Thrombosis in COVID-19 Patients: A Focused Analysis on D-Dimer, Homocysteine and Thromboembolism
Mohamed Abu-Farha,Salman Al-Sabah,Maha M. Hammad,Prashantha Hebbar,Arshad Channanath,Sumi Elsa John,Ibrahim Taher,Abdulrahman Almaeen,Amany A. Ghazy,Anwar Mohammad,Jehad Abubaker,Hossein Arefanian,Fahd Al-Mulla,Thangavel Alphonse Thanaraj +13 more
TL;DR: Genotyping COVID-19 patients for SNPs examined in this study will help identify those at greatest risk of complications linked to thrombosis, and uncover the genetic basis of the above conditions by examining genome-wide associations and tissue-specific gene expression to build a molecular network.
Journal ArticleDOI
Sequence and analysis of a whole genome from Kuwaiti population subgroup of Persian ancestry
Gaurav Thareja,Sumi Elsa John,Prashantha Hebbar,Kazem Behbehani,Thangavel Alphonse Thanaraj,Osama Alsmadi +5 more
TL;DR: The resource provides a starting point for designing large-scale genetic studies in Peninsula including Kuwait, and Persian population and positions the sequenced genome between Asian and European genomes in congruence with geographical location of the region.