S
Sumitra Bhattacharya
Researcher at University of Nebraska Medical Center
Publications - 20
Citations - 1196
Sumitra Bhattacharya is an academic researcher from University of Nebraska Medical Center. The author has contributed to research in topics: Stem cell & Cellular differentiation. The author has an hindex of 16, co-authored 20 publications receiving 1154 citations.
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Journal ArticleDOI
Neural stem cell properties of Müller glia in the mammalian retina: regulation by Notch and Wnt signaling.
Ani V. Das,Kavita Mallya,Xing Zhao,Faraz Ahmad,Sumitra Bhattacharya,Wallace B. Thoreson,Ganapati V. Hegde,Iqbal Ahmad +7 more
TL;DR: It is shown that Müller cells, when retrospectively enriched from the normal retina, display cardinal features of neural stem cells (NSCs), i.e., they self-renew and generate all three basic cell types of the CNS.
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Neural stem cells in the mammalian eye: types and regulation
TL;DR: The retinal and ciliary epithelium stem cells/progenitors appear to share similar signaling pathways that are emerging as important regulators of stem cells in general, yet, they are different in certain respects, such as in the potential to self-renew.
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Direct identification and enrichment of retinal stem cells/progenitors by Hoechst dye efflux assay.
Sumitra Bhattacharya,John D. Jackson,Ani V. Das,Wallace B. Thoreson,Charles A. Kuszynski,Jackson James,Shantaram S. Joshi,Iqbal Ahmad +7 more
TL;DR: The results demonstrate that the prospectively isolated retinal stem cells/progenitors and those enriched as SP cells from mitogen-exposed retinal cell culture may be similar in their properties and potential.
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Transplantation of ocular stem cells: the role of injury in incorporation and differentiation of grafted cells in the retina.
TL;DR: These findings demonstrate that injury-induced cues play a significant role in promoting the incorporation of ocular stem cells/progenitors regardless of their origin or their differentiation along specific retinal sublineage.
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Maintenance of retinal stem cells by Abcg2 is regulated by notch signaling.
TL;DR: It is demonstrated using retinal stem cells, that ABCG2 is the molecular determinant of SP cell phenotype of neural stem cells and plays an important role in their maintenance.