S
Sunam Mander
Researcher at Korea University
Publications - 10
Citations - 78
Sunam Mander is an academic researcher from Korea University. The author has contributed to research in topics: Cancer & Metastasis. The author has an hindex of 4, co-authored 6 publications receiving 40 citations.
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Journal ArticleDOI
The accessory proteins REEP5 and REEP6 refine CXCR1-mediated cellular responses and lung cancer progression.
Cho Rong Park,Dong Joo You,Sumi Park,Sunam Mander,Da Eun Jang,Su Cheong Yeom,Seong Hyun Oh,Curie Ahn,Sang Heon Lee,Jae Young Seong,Jong Ik Hwang +10 more
TL;DR: In A549 lung cancer cells, the depletion of REEP5 and REEP6 significantly reduced growth and invasion by downregulating IL-8-stimulated ERK phosphorylation, actin polymerization and the expression of genes related to metastasis.
Journal ArticleDOI
Nafamostat mesilate negatively regulates the metastasis of triple-negative breast cancer cells
Sunam Mander,Dong Joo You,Sumi Park,Dong Hwi Kim,Hyo Jeong Yong,Dong Sik Kim,Curie Ahn,Yun Hee Kim,Jae Young Seong,Jong Ik Hwang +9 more
TL;DR: Examination of the anti-cancer effects of nafamostat mesilate revealed that NM inhibits cell growth and metastasis of TNBC cells and indicated that NM is a multi-targeted drug that could be an adjunct therapy for TNBC treatment.
Journal ArticleDOI
SP-8356, a (1S)-(-)-verbenone derivative, exerts in vitro and in vivo anti-breast cancer effects by inhibiting NF-κB signaling.
Sunam Mander,Dong Hwi Kim,Huong Thi Nguyen,Hyo Jeong Yong,Kisoo Pahk,Eun Yeong Kim,Kiho Lee,Jae Young Seong,Won Ki Kim,Jong Ik Hwang +9 more
TL;DR: SP-8356 suppresses breast cancer progression through multimodal functions, including inhibition of NF-κB signaling and growth-related signaling pathways, and downregulation of many genes related to cancer invasion.
Journal ArticleDOI
Image-guided surgery with a new tumour-targeting probe improves the identification of positive margins
Masahide Goto,In-Sang Ryoo,Samer A Naffouje,Sunam Mander,Konstantin Christov,Jing Wang,Albert Green,Anne Shilkaitis,Tapas K. Das Gupta,Tohru Yamada +9 more
TL;DR: In this paper , the authors developed a unique near-infrared (NIR) fluorescence imaging probe, ICG-p28, composed of the clinically nontoxic tumour-targeting peptide p28 and the FDA-approved NIR dye indocyanine green (ICG).
Journal ArticleDOI
SP-8356, a (1S)-(-)-Verbenone Derivative, Inhibits the Growth and Motility of Liver Cancer Cells by Regulating NF-κB and ERK Signaling.
Dong Hwi Kim,Hyo Jeong Yong,Sunam Mander,Huong Thi Nguyen,Lan Phuong Nguyen,Hee Kyung Park,Hyo Kyeong Cha,Won Ki Kim,Jong Ik Hwang +8 more
TL;DR: In this paper, a verbenone derivative with anti-inflammatory activity, SP-8356, was investigated for its effect on the growth and migration of liver cancer cells by inducing apoptosis and suppressing the mobility and invasion ability.