S
Sung-Il Kim
Researcher at Pusan National University
Publications - 35
Citations - 1338
Sung-Il Kim is an academic researcher from Pusan National University. The author has contributed to research in topics: Rheumatoid arthritis & Arthritis. The author has an hindex of 15, co-authored 35 publications receiving 1223 citations. Previous affiliations of Sung-Il Kim include Kosin University.
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Journal ArticleDOI
Efficacy and safety of golimumab in patients with ankylosing spondylitis: results of a randomized, double-blind, placebo-controlled, phase III trial.
Robert D. Inman,John C. Davis,Désirée van der Heijde,Laura Diekman,Joachim Sieper,Sung-Il Kim,Michael Mack,J. Han,Sudha Visvanathan,Zhenhua Xu,Benjamin Hsu,A. Beutler,Jürgen Braun +12 more
TL;DR: Golimumab was effective and well tolerated in a large cohort of patients with ankylosing spondylitis during a 24-week study period.
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Enhanced T cell proliferative response to type II collagen and synthetic peptide CII (255-274) in patients with rheumatoid arthritis.
Ho-Youn Kim,Wan-Uk Kim,Mi-La Cho,Suk Kyeong Lee,Jeehee Youn,Sung-Il Kim,Wan-Hee Yoo,Jae-Ho Park,Jun-Ki Min,Sang-Heon Lee,Sung-Hwan Park,Chul-Soo Cho +11 more
TL;DR: T cell responses to CII or CII (255-274) were enhanced in RA, especially in early disease, suggesting that CII-reactive T cells play an important role in the pathogenesis of RA.
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Interleukin-21 promotes osteoclastogenesis in humans with rheumatoid arthritis and in mice with collagen-induced arthritis
Seung-Ki Kwok,Mi-La Cho,Mi-Kyung Park,Hye-Joa Oh,Jin-Sil Park,Yang-Mi Her,Seon-Yeong Lee,Jeehee Youn,Ji Hyeon Ju,Kyung Su Park,Sung-Il Kim,Ho-Youn Kim,Sung-Hwan Park +12 more
TL;DR: The data suggest that therapeutic strategies targeting IL-21 might be effective for the treatment of patients with RA, especially in preventing bone destruction and enhancing in vitro osteoclastogenesis.
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CD40 ligation of rheumatoid synovial fibroblasts regulates RANKL-mediated osteoclastogenesis: evidence of NF-kappaB-dependent, CD40-mediated bone destruction in rheumatoid arthritis.
Hak Yong Lee,Hyun Soon Jeon,Eun Kyung Song,Myung Kwan Han,Sung Il Park,Sang Il Lee,Hee Jin Yun,Jung Ryul Kim,Jong-Suk Kim,Yong Chul Lee,Sung-Il Kim,Hang Rae Kim,Jin-Young Choi,Insoo Kang,Ho-Youn Kim,Wan Hee Yoo,Wan Hee Yoo +16 more
TL;DR: Results indicate that CD40 ligation of RASFs induces RANKL expression mainly via NF-kappaB activation and also results in enhanced osteoclast formation, both of which might play important roles in bone and cartilage destruction in RA.
Journal ArticleDOI
Expression of TLR2, TLR4, and TLR9 in dermatomyositis and polymyositis
Geun-Tae Kim,Mi-La Cho,Young-Eun Park,Wan Hee Yoo,Jung-Hee Kim,Hye-Jwa Oh,Dae-Sung Kim,Seung-Hoon Baek,Sun Hee Lee,Jun-Hee Lee,Ho-Youn Kim,Sung-Il Kim +11 more
TL;DR: The results suggest that the involvement of TLR4 and TLR9 in immunopathogenesis of DM and PM might be connected with activation of CD4+ T cells.