S
Sunyoung Kim
Researcher at Seoul National University
Publications - 124
Citations - 6987
Sunyoung Kim is an academic researcher from Seoul National University. The author has contributed to research in topics: Gene expression & Gene. The author has an hindex of 37, co-authored 121 publications receiving 6619 citations. Previous affiliations of Sunyoung Kim include New Generation University College & Harvard University.
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MicroRNA maturation: stepwise processing and subcellular localization.
TL;DR: In vivo and in vitro evidence is presented that these clustered miRNAs are expressed polycistronically and are processed through at least two sequential steps, including the two processing steps and the nuclear export step, suggesting that the regulation of miRNA expression may occur at multiple levels.
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Temporal aspects of DNA and RNA synthesis during human immunodeficiency virus infection: evidence for differential gene expression.
TL;DR: A single-cycle growth condition for HIV in H9 cells, a human CD4+ lymphocyte line, is established and it is shown that viral DNA synthesis is as rapid as for other retroviruses, but viral RNA synthesis involves temporal alteration in the species that accumulate, presumably as a consequence of viral regulatory genes.
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Lack of a negative influence on viral growth by the nef gene of human immunodeficiency virus type 1
TL;DR: The data suggest that the Nef protein does not act as a negative factor, at least in the experimental systems employed in the studies, and is compared to two isogenic HIV-1 strains, one of which lacks nef expression and found little difference between them in in vitro growth.
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Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes
TL;DR: RNA was analyzed in the early phase of a one-step growth cycle of HIV-1 infection in T-lymphoid and monocytic cell lines by using PCR amplification of in vitro-synthesized viral cDNAs and found that expression of at least small amounts of the singly spliced message could occur before the accumulation of Rev.
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Identification of sequences in a yeast histone promoter involved in periodic transcription
TL;DR: Sequences between a pair of divergently transcribed histone genes in Saccharomyces cerevisiae are able to confer periodic transcription during the cell cycle, and negative regulation may be the predominant form of cell-cycle control.