S
Surendra Kumar
Researcher at Gachon University
Publications - 53
Citations - 818
Surendra Kumar is an academic researcher from Gachon University. The author has contributed to research in topics: Quantitative structure–activity relationship & Docking (molecular). The author has an hindex of 12, co-authored 47 publications receiving 565 citations. Previous affiliations of Surendra Kumar include Hatch Ltd & Northern India Engineering College.
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Journal Article
Undernutrition & childhood morbidities among tribal preschool children.
TL;DR: The findings of the present study revealed the widespread prevalence of undernutrition among pre-school tribal children and highlight a need for an integrated approach towards improving the child health as well as nutritional status in this area.
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Lean tool selection in a die casting unit: a fuzzy-based decision support heuristic
TL;DR: In this article, a case study related to a die casting unit has been taken, where a hierarchy related to the decision problem has been developed to select the value stream mapping tools.
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Molecular Insights into the Interaction of RONS and Thieno[3,2-c]pyran Analogs with SIRT6/COX-2: A Molecular Dynamics Study.
Dharmendra Kumar Yadav,Surendra Kumar,Saloni,Sanjeev Misra,Lalit Yadav,Mahesh Kumar Teli,Praveen Sharma,Sandeep Chaudhary,Naresh Kumar,Eun Ha Choi,Hyung Sik Kim,Mi-hyun Kim +11 more
TL;DR: This work studied the interaction of thieno[3,2-c]pyran analogs and RONS species with SIRT6 and COX-2 through the use of molecular docking and molecular dynamic simulations to reveal the importance of hydrophobic and hydrophilic amino acid residues for the stability of the protein-drug complex.
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Molecular docking, QSAR and ADMET studies of withanolide analogs against breast cancer
Dharmendra Kumar Yadav,Surendra Kumar,Saloni,Harpreet Singh,Mi-hyun Kim,Praveen Sharma,Sanjeev Misra,Feroz Khan +7 more
TL;DR: A quantitative structure activity relationship (QSAR) model was developed by a forward stepwise multiple linear regression method to predict the activity of withanolide analogs against human breast cancer and the results of the present study may help in the designing of lead compound with improved activity.
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Molecular dynamic simulations of oxidized skin lipid bilayer and permeability of reactive oxygen species.
TL;DR: The measured free energy profile for different ROS across the peroxidized lipid bilayer showed that the increase in lipid peroxidation resulted in breaching barrier decrease for all species, allowing easy traversal of the membrane.