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Susan J. Wilson
Researcher at University of Southampton
Publications - 131
Citations - 12962
Susan J. Wilson is an academic researcher from University of Southampton. The author has contributed to research in topics: Asthma & Eosinophil. The author has an hindex of 54, co-authored 130 publications receiving 12279 citations. Previous affiliations of Susan J. Wilson include Loughborough University & Southampton General Hospital.
Papers
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Journal ArticleDOI
Effect of an inhaled corticosteroid on airway inflammation and symptoms in asthma.
Ratko Djukanovic,John W Wilson,KM Britten,Susan J. Wilson,Andrew F. Walls,William R. Roche,Peter H. Howarth,Stephen T. Holgate +7 more
TL;DR: It is suggested that the beneficial effect of inhaled corticosteroids in asthma may be attributed to their antiinflammatory action in the bronchial mucosa.
Journal ArticleDOI
Effects of Treatment with Anti-immunoglobulin E Antibody Omalizumab on Airway Inflammation in Allergic Asthma
Ratko Djukanovic,Susan J. Wilson,Monica Kraft,Nizar N. Jarjour,Mark D. Steel,K. Fan Chung,Weibin Bao,Angel FowlerTaylor,John G. Matthews,William W. Busse,Stephen T. Holgate,John V. Fahy +11 more
TL;DR: The lack of effect of omalizumab on methacholine responsiveness suggests that IgE or eosinophils may not be causally linked to airway hyperresponsiveness to Methacholine in mild to moderate asthma.
Journal ArticleDOI
Alveolar Tissue Inflammation in Asthma
TL;DR: It is suggested that eosinophils and macrophages accumulate to a greater extent in the alveolar tissue and these changes contribute more to the variation in lung function compared with inflammation in the more proximal tissue.
Journal Article
Immunolocalization of cytokines in the nasal mucosa of normal and perennial rhinitic subjects. The mast cell as a source of IL-4, IL-5, and IL-6 in human allergic mucosal inflammation.
P. Bradding,I. Feather,Susan J. Wilson,P. G. Bardin,C H Heusser,Stephen T. Holgate,Peter H. Howarth +6 more
TL;DR: Findings indicate that the mast cell is an important source of preformed cytokines and as such may contribute to the chronicity of the mucosal inflammation that characterizes allergic rhinitis.
Journal ArticleDOI
Epithelial-mesenchymal interactions in the pathogenesis of asthma.
Stephen T. Holgate,Donna E. Davies,Peter M. Lackie,Susan J. Wilson,Sarah M. Puddicombe,James L. Lordan +5 more
TL;DR: It is proposed that impaired epithelial repair cooperates with the TH2 environment to shift the set point for communication within the trophic unit and leads to myofibroblast activation, excessive matrix deposition, and production of mediators that propagate and amplify the remodeling responses throughout the airway wall.