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Susan M. Edgerton
Researcher at University of Oklahoma
Publications - 21
Citations - 2687
Susan M. Edgerton is an academic researcher from University of Oklahoma. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 17, co-authored 21 publications receiving 2646 citations. Previous affiliations of Susan M. Edgerton include Northwestern University & University of Oklahoma Health Sciences Center.
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Journal ArticleDOI
Accumulation of p53 Tumor Suppressor Gene Protein: An Independent Marker of Prognosis in Breast Cancers
Ann D. Thor,Dan H. Moore,Susan M. Edgerton,Ernest S. Kawasaki,Ellen Reihsaus,Henry T. Lynch,Joseph N. Marcus,Laurent H. Schwartz,Ling Chun Chen,Brian H. Mayall,Helene S. Smith +10 more
TL;DR: Immunohistochemically detected p53 protein accumulation was an independent marker of shortened survival and was seen more often in familial than in sporadic carcinomas, suggesting a correlation between p53protein accumulation and p53 gene mutation.
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erbB-2, p53, and Efficacy of Adjuvant Therapy in Lymph Node-Positive Breast Cancer
Ann D. Thor,Ann D. Thor,Donald A. Berry,Daniel R. Budman,Hyman B. Muss,Timothy E. Kute,I. Craig Henderson,Maurice Barcos,Constance Cirrincione,Susan M. Edgerton,Craig Allred,Larry Norton,Edison T. Liu,Edison T. Liu +13 more
TL;DR: The hypothesis that patients whose breast tumors exhibit high erbB-2 expression benefit from dose-intensive CAF should be further validated before clinical implementation.
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Activation (Tyrosine Phosphorylation) of ErbB-2 (HER-2/neu): A Study of Incidence and Correlation With Outcome in Breast Cancer
Ann D. Thor,Shuqing Liu,Susan M. Edgerton,Dan H. Moore,K.M. Kasowitz,Christopher C. Benz,David F. Stern,Michael P. DiGiovanna +7 more
TL;DR: It was found that either P-ErbB-2 expression or high (> or = 80%) ErbB -2 expression provided the most significant prognostic value in node-positive cases by multivariate analyses.
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Invasive micropapillary carcinoma of the breast: A prognostic study☆
Michael Paterakos,Michael Paterakos,William G. Watkin,William G. Watkin,Susan M. Edgerton,Susan M. Edgerton,Dan H. Moore,Dan H. Moore,Ann D. Thor,Ann D. Thor +9 more
TL;DR: Breast cancer patients with pure IMC histology showed survival rates similar to those of other patients with equivalent numbers of lymph node metastases, and univariate analyses showed a strong association between IMC Histology and shortened survival.
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Stress Response Protein (srp–27) Determination in Primary Human Breast Carcinomas: Clinical, Histologic, and Prognostic Correlations
Ann D. Thor,Christopher C. Benz,Dan H. Moore,Eric S. Goldman,Susan M. Edgerton,Jacques Landry,Laurent H. Schwartz,Brian Mayall,Eileen Hickey,Lee A. Weber +9 more
TL;DR: The Cox proportional hazards model confirmed the independent prognostic significance of nodal involvement, T stage, and ER content but failed to recognize srp-27 overexpression as a significant independent parameter predictive of patient outcome in the patient population as a whole.