S
Susanna K. Tan
Researcher at Cedars-Sinai Medical Center
Publications - 5
Citations - 2320
Susanna K. Tan is an academic researcher from Cedars-Sinai Medical Center. The author has contributed to research in topics: Medicine & Hepatitis B virus. The author has an hindex of 1, co-authored 1 publications receiving 1879 citations.
Papers
More filters
Journal ArticleDOI
Compassionate Use of Remdesivir for Patients with Severe Covid-19.
Jonathan Grein,Norio Ohmagari,Daniel Shin,George Diaz,Erika Asperges,Antonella Castagna,Torsten Feldt,Gary M. Green,Margaret L. Green,François-Xavier Lescure,Emanuele Nicastri,Rentaro Oda,Kikuo Yo,Eugenia Quiros-Roldan,Alex Studemeister,John Redinski,Seema Ahmed,Jorge Bernett,Daniel Chelliah,Danny Chen,Shingo Chihara,Stuart H. Cohen,Jennifer Cunningham,Antonella D’Arminio Monforte,Saad Ismail,Hideaki Kato,Giuseppe Lapadula,Erwan L’Her,Toshitaka Maeno,Sumit Majumder,Marco Massari,Marta Mora-Rillo,Yoshikazu Mutoh,Duc Nguyen,Ewa Verweij,Alexander Zoufaly,Anu Osinusi,Adam DeZure,Yang Zhao,Lijie Zhong,Anand Chokkalingam,Emon Elboudwarej,Laura Telep,Leighann Timbs,Ilana Henne,Scott Sellers,Huyen Cao,Susanna K. Tan,Lucinda Winterbourne,Polly Desai,Robertino Mera,Anuj Gaggar,Robert P. Myers,Diana M. Brainard,Richard Childs,Timothy Flanigan +55 more
TL;DR: In this cohort of patients hospitalized for severe Covid-19 who were treated with compassionate-use remdesivir, clinical improvement was observed in 36 of 53 patients, and Measurement of efficacy will require ongoing randomized, placebo-controlled trials of remdesavir therapy.
Journal ArticleDOI
Safety and efficacy of the oral TLR8 agonist selgantolimod in individuals with chronic hepatitis B under viral suppression
Edward Gane,P. Rod Dunbar,Anna E. S. Brooks,Fan Zhang,Diana Chen,Jeffrey Wallin,Nicholas van Buuren,Priyanka Arora,G. Fletcher,Susanna K. Tan,Jenny C. Yang,Anuj Gaggar,Shyam Kottilil,Lydia Tang +13 more
TL;DR: Selgantolimod (GS-9688) is a toll-like receptor 8 (TLR8) agonist that suppresses hepatitis B virus (HBV) in vitro as mentioned in this paper .
Journal ArticleDOI
Secreted hepatitis B virus splice variants differ by HBV genotype and across phases of chronic hepatitis B infection
Olivia Maslac,Josef Wagner,V. Sozzi,Hugh Mason,Jenny Svarovskaia,Susanna K. Tan,Anuj Gaggar,Stephen Locarnini,Lilly Yuen,Margaret Littlejohn,Peter Revill +10 more
TL;DR: The increased levels of HBV splice variants detected in CHB phase II patients compared with the higher replicative Phase I in particular warrants further investigation.
Journal ArticleDOI
Hepatitis B virus haplotype number at baseline is a predictive marker of functional cure during antiviral therapy for patients with genotypes A and D HBeAg‐positive chronic hepatitis B
Josef Wagner,Lilly Yuen,Margaret Littlejohn,V. Sozzi,Kathy Jackson,Ross Martin,Thomas Aeschbacher,Vithika Suri,Susanna K. Tan,Becket Feierbach,Anuj Gaggar,Patrick Marcellin,Maria Buti Ferret,Harry L.A. Janssen,Edward Gane,Niamh Meagher,David Price,Darren J. Wong,Alexander J. Thompson,Peter Revill +19 more
TL;DR: In this article , the authors investigated associations between hepatitis B virus (HBV) genome length haplotype number (HN) at baseline in subjects with HBeAg positive chronic hepatitis B (CHB) and the likelihood of achieving functional cure during direct-acting antiviral therapy.
Journal ArticleDOI
Hepatitis B virus splice variants are associated with reduced likelihood of functional cure and differ across phases of chronic hepatitis B infection
Olivia Maslac,Josef Wagner,V. Sozzi,Hugh Mason,Evguenia S. Svarovskaia,Susanna K. Tan,Anuj Gaggar,Stephen Locarnini,Lilly Yuen,Margaret Littlejohn,Peter Revill +10 more