H
Harry L.A. Janssen
Researcher at University Health Network
Publications - 526
Citations - 24341
Harry L.A. Janssen is an academic researcher from University Health Network. The author has contributed to research in topics: Hepatitis B & Hepatitis B virus. The author has an hindex of 76, co-authored 470 publications receiving 19957 citations. Previous affiliations of Harry L.A. Janssen include Erasmus University Medical Center & Erasmus University Rotterdam.
Papers
More filters
Journal ArticleDOI
Hepatitis B virus infection
Man-Fung Yuen,Ding-Shinn Chen,Ding-Shinn Chen,Geoffrey Dusheiko,Harry L.A. Janssen,Daryl T.-Y. Lau,Stephen Locarnini,Marion G. Peters,Ching-Lung Lai +8 more
TL;DR: This Primer addresses several aspects of HBV infection, including epidemiology, immune pathophysiology, diagnosis, prevention and management, including antiviral agents that directly act on viral replication and immunomodulators, such as interferon therapy.
Journal ArticleDOI
Risk of hepatocellular carcinoma in chronic hepatitis B: Assessment and modification with current antiviral therapy
George V. Papatheodoridis,Henry Lik-Yuen Chan,Bettina E. Hansen,Harry L.A. Janssen,Harry L.A. Janssen,Pietro Lampertico +5 more
TL;DR: Overall, data indicate that with the current, potent NAs, HCC risk can be reduced but not eliminated, probably due to risk factors that are not amenable to change by antiviral therapy, or events that may have taken place before treatment initiation.
Journal ArticleDOI
Levels of alkaline phosphatase and bilirubin are surrogate end points of outcomes of patients with primary biliary cirrhosis: An international follow-up study
Willem J Lammers,Henk R. van Buuren,Gideon M. Hirschfield,Harry L.A. Janssen,Pietro Invernizzi,Andrew Mason,Cyriel Y. Ponsioen,Annarosa Floreani,Christophe Corpechot,Marlyn J. Mayo,Pier Maria Battezzati,Albert Parés,Frederik Nevens,Andrew K. Burroughs,Kris V. Kowdley,Palak J. Trivedi,Teru Kumagi,Teru Kumagi,Angela M. Cheung,Ana Lleo,Mohamad Imam,Kirsten Boonstra,Nora Cazzagon,I. Franceschet,Raoul Poupon,Llorenç Caballería,G. Pieri,Pushpjeet Kanwar,Keith D. Lindor,Keith D. Lindor,Bettina E. Hansen +30 more
TL;DR: Levels of alkaline phosphatase and bilirubin can predict outcomes (liver transplantation or death) of patients with PBC and might be used as surrogate end points in therapy trials.
Journal ArticleDOI
The impact of JAK2 and MPL mutations on diagnosis and prognosis of splanchnic vein thrombosis. A report on 241 cases
Jean-Jacques Kiladjian,Francisco Cervantes,Franck W. G. Leebeek,Christophe Marzac,Bruno Cassinat,Sylvie Chevret,Dominique Cazals-Hatem,Aurélie Plessier,Juan Carlos García-Pagán,Sarwa Darwish Murad,Sebastián Raffa,Harry L.A. Janssen,Claude Gardin,Sophie Cereja,Carole Tonetti,Stéphane Giraudier,Bertrand Condat,Nicole Casadevall,Pierre Fenaux,Dominique Valla +19 more
TL;DR: The results suggest that JAK2V617F testing should replace BM investigations as initial test for MPD in patients with SVT, and that current therapy appears to offset deleterious effects of MPD on the medium-term outcome.
Journal ArticleDOI
PAGE-B predicts the risk of developing hepatocellular carcinoma in Caucasians with chronic hepatitis B on 5-year antiviral therapy
George V. Papatheodoridis,George N. Dalekos,Vana Sypsa,Cihan Yurdaydin,Maria Buti,John Goulis,Jose Luis Calleja,Heng Chi,Spilios Manolakopoulos,G. Mangia,Nikolaos K. Gatselis,Onur Keskin,Savvoula Savvidou,Juan de la Revilla,Bettina E. Hansen,Ioannis Vlachogiannakos,Kostantinos Galanis,Ramazan Idilman,Massimo Colombo,Rafael Esteban,Harry L.A. Janssen,Harry L.A. Janssen,Pietro Lampertico +22 more
TL;DR: In this paper, the authors developed a risk score for hepatocellular carcinoma (HCC) developed in Asians offer poor-moderate predictability in Caucasian patients with chronic hepatitis B (CHB).