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Sushruta Koppula

Researcher at Konkuk University

Publications -  101
Citations -  2473

Sushruta Koppula is an academic researcher from Konkuk University. The author has contributed to research in topics: Inflammasome & Oxidative stress. The author has an hindex of 26, co-authored 97 publications receiving 2064 citations. Previous affiliations of Sushruta Koppula include Khon Kaen University & Seoul National University.

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The Role of Free Radicals in the Aging Brain and Parkinson’s Disease: Convergence and Parallelism

Hemant Kumar, +6 more
- 21 Aug 2012 - 
TL;DR: This work enumerates the common link between aging and PD at the cellular level with special reference to oxidative damage caused by free radicals, and reduces activity of superoxide dismutase, catalase and glutathione with aging might be correlated with the increased incidence of PD.
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Adaptogenic and nootropic activities of aqueous extract of Vitis vinifera (grape seed): an experimental study in rat model

Satyanarayana Sreemantula, +6 more
- 19 Jan 2005 - 
TL;DR: The present study provides scientific support for the antistress (adaptogenic), antioxidant and nootropic activities of V. vinifera seed extract and substantiate the traditional claims for the usage of grape fruits and seeds in stress induced disorders.
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Inhibitors of microglial neurotoxicity: focus on natural products.

Dong-Kug Choi, +2 more
- 25 Jan 2011 - 
TL;DR: Future works should focus on the discovery of novel drug targets that specifically mediate microglial neurotoxicity rather than neuroprotection, and development of new drugs based on these targets may require a better understanding of microglia biology and neuroinflammation at the molecular, cellular, and systems levels.
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Reactive oxygen species and inhibitors of inflammatory enzymes, NADPH oxidase, and iNOS in experimental models of Parkinson's disease.

Sushruta Koppula, +3 more
- 22 Apr 2012 - 
TL;DR: Recently developed agents and patents claimed as inhibitors of NADPH oxidase and iNOS enzymes in experimental models of PD are summarized to represent a therapeutic target to reduce neuronal degeneration seen in PD.
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α-Asarone attenuates microglia-mediated neuroinflammation by inhibiting NF kappa B activation and mitigates MPTP-induced behavioral deficits in a mouse model of Parkinson's disease.

Byung-Wook Kim, +10 more
- 01 Oct 2015 - 
TL;DR: Data demonstrate that α-asarone is a promising neuroprotective agent that should be further evaluated and developed for future prevention and treatment of microglia-mediated neuroinflammatory conditions including PD.