S
Svetlana Kotliarova
Researcher at National Institutes of Health
Publications - 27
Citations - 4456
Svetlana Kotliarova is an academic researcher from National Institutes of Health. The author has contributed to research in topics: DNA methylation & Glioma. The author has an hindex of 22, co-authored 27 publications receiving 4184 citations. Previous affiliations of Svetlana Kotliarova include RIKEN Brain Science Institute & University of Tokyo.
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Journal ArticleDOI
SnapShot: glioblastoma multiforme.
TL;DR: This paper presents a new method to identify and isolate viable BTSCs that meets STEMCELL Technologies’ stringent quality control standards, including rigorous performance testing using primary cells.
Journal ArticleDOI
Detailed longitudinal sampling of glioma stem cells in situ reveals Chr7 gain and Chr10 loss as repeated events in primary tumor formation and recurrence.
Mehmet Baysan,Kevin D. Woolard,Margaret C. Cam,Wei Zhang,Hua Song,Svetlana Kotliarova,Demosthenes Balamatsias,Amanda G. Linkous,Susie Ahn,Jennifer Walling,Galina I. Belova,Howard A. Fine +11 more
TL;DR: An extensive dataset for a GBM case via the generation of polyclonal and monoclonal glioma stem cell lines is developed, and from multiple sections of distant tumor locations of the deceased patient's brain following tumor recurrence is developed.
Journal ArticleDOI
A Core Regulatory Circuit in Glioblastoma Stem Cells Links MAPK Activation to a Transcriptional Program of Neural Stem Cell Identity
Gregory Riddick,Svetlana Kotliarova,Virginia Rodriguez,Hong Sug Kim,Amanda G. Linkous,Andrew J. Storaska,Susie Ahn,Jennifer Walling,Galina I. Belova,Howard A. Fine +9 more
TL;DR: It is demonstrated how known genomic alterations in glioma that induce constitutive activation of MAPK are transcriptionally linked to master regulators essential for neural stem cell identify.
Journal ArticleDOI
Fluorescent multiplex PCR--fast method for autosomal dominant spinocerebellar ataxias screening.
P. O. Bauer,P. O. Bauer,Svetlana Kotliarova,Vaclav Matoska,Z. Musova,P. Hedvicakova,A. Boday,Aleš Tomek,Nobuyuki Nukina,P. Goetz +9 more
TL;DR: A fast and efficient screening method based on touchdown multiplex PCR with fluorescent labelled primers for the most common types of SCAs (SCA 1, 2, 3, and 7) that has been reliable in 113 probands tested and might be used as a tip for designing other SCA screening sets.
Proceedings ArticleDOI
Age-Specific Signatures of Glioblastoma at the Genomic, Genetic, and Epigenetic levels
Serdar Bozdag,Aiguo Li,Gregory Riddick,Yuri Kotliarov,Mehmet Baysan,Fabio M. Iwamoto,Margaret C. Cam,Svetlana Kotliarova,Howard A. Fine +8 more
TL;DR: Major age-specific signatures at all levels are found including age- specific hypermethylation in polycomb group protein target genes and the upregulation of angiogenesis-related genes in older GBMs.