S
Syed Khalid Yousuf
Researcher at Council of Scientific and Industrial Research
Publications - 59
Citations - 983
Syed Khalid Yousuf is an academic researcher from Council of Scientific and Industrial Research. The author has contributed to research in topics: Catalysis & Reagent. The author has an hindex of 19, co-authored 56 publications receiving 817 citations. Previous affiliations of Syed Khalid Yousuf include Academy of Scientific and Innovative Research.
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Importance and synthesis of benzannulated medium-sized and macrocyclic rings (BMRs)
TL;DR: In this article, the authors highlight the importance of benzannulated medium-sized and macrocyclic rings (BMRs) and the strategies developed over the years for their synthesis.
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PAWR-mediated suppression of BCL2 promotes switching of 3-azido withaferin A (3-AWA)-induced autophagy to apoptosis in prostate cancer cells.
Bilal Rah,Reyaz ur Rasool,Debasis Nayak,Syed Khalid Yousuf,Debaraj Mukherjee,Lekha Dinesh Kumar,Anindya Goswami +6 more
TL;DR: Evidence is provided that 3-AWA is a strong anticancer candidate to abrogate protective autophagy and enhanced chemosensitivity by sensitizing prostate cancer cells to apoptosis through induction of PAWR endorsing its therapeutic potential.
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Cell wall: A versatile fountain of drug targets in Mycobacterium tuberculosis
Zubair Shanib Bhat,Muzafar Ahmad Rather,Mubashir Maqbool,Hafiz Ul Lah,Syed Khalid Yousuf,Zahoor Ahmad +5 more
TL;DR: Novel sets of enzyme inhibitors that disrupt mycobacterium tuberculosis cell wall biosynthetic pathway are highlighted to highlight new potent inhibitors with least cytotoxicity and better efficacy against emergence of drug resistance till date.
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Ring A structural modified derivatives of withaferin A and the evaluation of their cytotoxic potential.
Syed Khalid Yousuf,Rabiya Majeed,Mudassier Ahmad,Payare L. Sangwan,Basant Purnima,A.K. Saxsena,Krishan Avtar Suri,Debaraj Mukherjee,Subhash C. Taneja +8 more
TL;DR: Modifications of 3-azido analogue with various alkynes under Husigen's cycloaddition conditions generated a variety of triazole derivatives with reduced cytotoxicity.
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α-pyrones: Small molecules with versatile structural diversity reflected in multiple pharmacological activities-an update.
Zubair Shanib Bhat,Zubair Shanib Bhat,Muzafar Ahmad Rather,Mubashir Maqbool,Hafiz Ul Lah,Syed Khalid Yousuf,Syed Khalid Yousuf,Zahoor Ahmad,Zahoor Ahmad +8 more
TL;DR: This review focuses on the distinctive chemotherapeutic activities of 2-pyrones as anti-HIV, anti-TB and anti-cancer agents followed by their potential role against neurodegeneration, hypercholesterolemia, microbial infections, chronic obstructive lung disease, inflammation, antinociception and immunomodulation.