S
Szilárd Varga
Researcher at Hungarian Academy of Sciences
Publications - 19
Citations - 1387
Szilárd Varga is an academic researcher from Hungarian Academy of Sciences. The author has contributed to research in topics: Bifunctional & Organocatalysis. The author has an hindex of 9, co-authored 16 publications receiving 1285 citations. Previous affiliations of Szilárd Varga include Chemical Research Center of the Hungarian Academy of Sciences.
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Highly enantioselective conjugate addition of nitromethane to chalcones using bifunctional cinchona organocatalysts.
TL;DR: Cinchona alkaloid-derived chiral bifunctional thiourea organocatalysts were synthesized and applied in the Michael addition between nitromethane and chalcones with high ee and chemical yields.
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Epi-Cinchona Based Thiourea Organocatalyst Family as an Efficient Asymmetric Michael Addition Promoter: Enantioselective Conjugate Addition of Nitroalkanes to Chalcones and α,β-Unsaturated N-Acylpyrroles
TL;DR: A small set of easily available epi-cinchona based thiourea organocatalysts have been synthesized and tested in enantioselective addition of nitroalkanes to chalcones, and the extension of this methodology was further explored to encompass alpha,beta-unsaturated N-acylpyrroles, as a chalcone mimic.
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Edge‐to‐Face CH/π Aromatic Interaction and Molecular Self‐Recognition in epi‐Cinchona‐Based Bifunctional Thiourea Organocatalysis
TL;DR: The impact of cooperativity between intermolecular interactions is demonstrated by the molecular self-recognition properties of highly enantioselective epi-cinchona bifunctional thiourea organocatalysts.
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Thiourea Derivatives as Brønsted Acid Organocatalysts
TL;DR: In this paper, the authors showed that the catalytic effect is related to stabilizing double hydrogen-bonding interactions between the thiourea and the alcohol, which promote the attack on 3,4-dihydro-2H-pyran (DHP) (hydrogen bonding mechanism).
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Double diastereocontrol in bifunctional thiourea organocatalysis: iterative Michael-Michael-Henry sequence regulated by the configuration of chiral catalysts.
TL;DR: The results suggest that the bifunctional thioureas can have synthetic limitations in multicomponent domino or autotandem catalysis and a means to exploit this behavior is provided.