T
T Pietiläinen
Researcher at University of Eastern Finland
Publications - 8
Citations - 507
T Pietiläinen is an academic researcher from University of Eastern Finland. The author has contributed to research in topics: Breast cancer & Mitotic index. The author has an hindex of 8, co-authored 8 publications receiving 499 citations.
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Apoptosis suppressing protein bcl-2 is expressed in well-differentiated breast carcinomas with favourable prognosis.
TL;DR: In multivariate analysis, bcl‐2 expression had no independent prognostic value in the entire cohort or in axillary lymph node‐negative breast carcinomas, whereas it was a weakindependent prognostic factor in axilla lymph nodes‐positive breast carcinoma.
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Expression of retinoblastoma gene protein (Rb) in breast cancer as related to established prognostic factors and survival.
TL;DR: The results show that the tumour suppressor gene Rb participates in the growth regulation of breast cancer cells in vivo, but immunohistochemical assessment of the expression of Rb protein has no prognostic significance in clinical breast cancer over already established prognostic factors.
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p22/WAF1 expression in human colorectal carcinoma: association with p53, transcription factor AP-2 and prognosis.
K M Ropponen,Jari Kellokoski,Pertti Lipponen,T Pietiläinen,Eskelinen M,Esko Alhava,Veli-Matti Kosma +6 more
TL;DR: The results suggest that the immunohistochemical detection of cyclin-dependent kinase inhibitor p21 could be used to predict more precisely the outcome of colorectal cancer patients.
Journal Article
Reduced Nuclear Expression of Transcription Factor AP-2 Associates with Aggressive Breast Cancer
Johanna M. Pellikainen,Vesa Kataja,K M Ropponen,Jari Kellokoski,T Pietiläinen,Jan Böhm,Matti Eskelinen,Veli-Matti Kosma +7 more
TL;DR: AP-2 seems to have a protective role in breast cancer and was associated with disease progression and increased metastatic capability of the tumor, and reduced nuclear AP-2 expression independently predicted elevated risk of recurrent disease in Breast cancer.
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The important prognostic value of Ki-67 expression as determined by image analysis in breast cancer
TL;DR: Ki-67 expression could be an important prognostic determinant in breast cancer because of the evident loss of the predictive power of tumour size in the 1990s, and the prognostic value of Ki-67expression may even be accentuated in the currently diagnosed small breast carcinomas.