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T Waddell

Researcher at University of Dundee

Publications -  11
Citations -  1305

T Waddell is an academic researcher from University of Dundee. The author has contributed to research in topics: Skeletal muscle & Anabolism. The author has an hindex of 5, co-authored 8 publications receiving 1223 citations.

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Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle

TL;DR: It is demonstrated that EAA stimulate MPS independently of increased insulin availability, and in the elderly, a deficit in MPS in the basal state is unlikely; and the decreased sensitivity and responsiveness of MPS to EAA, associated with decrements in the expression and activation of components of anabolic signaling pathways, are probably major contributors to the failure of muscle maintenance inThe elderly.
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No effect of creatine supplementation on human myofibrillar and sarcoplasmic protein synthesis after resistance exercise.

TL;DR: Creatine supplementation increased muscle total creatine by approximately 21% and exercise increased the synthetic rates of myofibrillar and sarcoplasmic proteins by two- to threefold, and leg phenylalanine balance became more positive, but creatine was without any anabolic effect.
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Greater ectopic fat deposition and liver fibroinflammation and lower skeletal muscle mass in people with type 2 diabetes

TL;DR: In this paper , the authors investigated differences in visceral adiposity, ectopic fat accumulation, body composition, and relevant biomarkers between people with and without Type 2 diabetes (T2D).