T
T Waddell
Researcher at University of Dundee
Publications - 11
Citations - 1305
T Waddell is an academic researcher from University of Dundee. The author has contributed to research in topics: Skeletal muscle & Anabolism. The author has an hindex of 5, co-authored 8 publications receiving 1223 citations.
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Journal ArticleDOI
Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle
Daniel J. Cuthbertson,Kenneth Smith,Kenneth Smith,John A. Babraj,Graham P. Leese,T Waddell,Philip J. Atherton,Philip J. Atherton,Henning Wackerhage,Peter M. Taylor,M. J. Rennie,M. J. Rennie +11 more
TL;DR: It is demonstrated that EAA stimulate MPS independently of increased insulin availability, and in the elderly, a deficit in MPS in the basal state is unlikely; and the decreased sensitivity and responsiveness of MPS to EAA, associated with decrements in the expression and activation of components of anabolic signaling pathways, are probably major contributors to the failure of muscle maintenance inThe elderly.
Journal ArticleDOI
No effect of creatine supplementation on human myofibrillar and sarcoplasmic protein synthesis after resistance exercise.
Magali Louis,Jacques Poortmans,Marc Francaux,Jacques Berré,Nathalie Boisseau,Eric Brassine,Daniel J. Cuthbertson,Kenneth Smith,John A. Babraj,T Waddell,Michael J. Rennie +10 more
TL;DR: Creatine supplementation increased muscle total creatine by approximately 21% and exercise increased the synthetic rates of myofibrillar and sarcoplasmic proteins by two- to threefold, and leg phenylalanine balance became more positive, but creatine was without any anabolic effect.
Journal ArticleDOI
Creatine supplementation has no effect on human muscle protein turnover at rest in the postabsorptive or fed states.
Magali Louis,Jacques Poortmans,Marc Francaux,Eric Hultman,Jacques Berré,Nathalie Boisseau,Vernon R. Young,Kenneth Smith,Wolfram Meier-Augenstein,John A. Babraj,T Waddell,Michael J. Rennie +11 more
TL;DR: Any increase in muscle mass accompanying creatine supplementation must be associated with increased physical activity, and creatine had no effect on turnover in the postabsorptive or fed states.
Journal ArticleDOI
Greater ectopic fat deposition and liver fibroinflammation and lower skeletal muscle mass in people with type 2 diabetes
T Waddell,Alexandre Bagur,Diogo Cunha,Helena Thomaides-Brears,Rajarshi Banerjee,Daniel J. Cuthbertson,Emily Brown,Kenneth Cusi,Jean-Pierre Després,Michael Brady +9 more
TL;DR: In this paper , the authors investigated differences in visceral adiposity, ectopic fat accumulation, body composition, and relevant biomarkers between people with and without Type 2 diabetes (T2D).