Taiji Ito

TL;DR: It is shown that activation protein 1 (AP-1) activates the miR-21 transcription in conjugation with the SWI/SNF complex, after PMA stimulation, through the conserved AP-1 and PU.1 binding sites in the promoter identified here.

TL;DR: It is shown that BAF60a, a subunit of the SWI·SNF chromatin remodeling complex, is a determinant of the transactivation potential of Fos/Jun dimers.

TL;DR: The data suggest that fibroblasts may store VEGF in a latent state in the extracellular environment for urgent use in angiogenesis, resulting in tumor-selective utilization of fibroblast-derived V EGF.

TL;DR: It is shown here that these Brm-deficient human tumor cell lines carry a functional Brm gene, and all of the treated cells showed prolonged induction of Brm expression after the removal of HDAC inhibitors, and acquired the ability to maintain retroviral gene expression.

TL;DR: Stable prepackaging cell lines which can be converted into packaging cell lines for high-titer vesicular stomatitis virus G protein (VSV-G)-pseudotyped retrovirus vectors by the introduction of Cre recombinase-expressing adenovirus are reported on.