T
Takaaki Tokito
Researcher at Kurume University
Publications - 74
Citations - 5915
Takaaki Tokito is an academic researcher from Kurume University. The author has contributed to research in topics: Lung cancer & Medicine. The author has an hindex of 12, co-authored 56 publications receiving 4130 citations.
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Journal ArticleDOI
Durvalumab after Chemoradiotherapy in Stage III Non–Small-Cell Lung Cancer
Scott J. Antonia,A. Villegas,Davey B. Daniel,David Vicente,Shuji Murakami,Rina Hui,Takashi Yokoi,Alberto Chiappori,Ki Hyeong Lee,Maike de Wit,Byoung Chul Cho,M. Bourhaba,Xavier Quantin,Takaaki Tokito,Tarek Mekhail,David Planchard,Young-Chul Kim,Christos S. Karapetis,Sandrine Hiret,Gyula Ostoros,Kaoru Kubota,Jhanelle E. Gray,Luis Paz-Ares,Javier de Castro Carpeño,Catherine Wadsworth,Giovanni Melillo,Haiyi Jiang,Y. Huang,Phillip A. Dennis,Mustafa Ozguroglu,Pacific Investigators +30 more
TL;DR: Progression‐free survival was significantly longer with durvalumab than with placebo, and safety was similar between the groups, and the secondary end points also favored durvalsumab.
Journal ArticleDOI
Overall Survival with Durvalumab after Chemoradiotherapy in Stage III NSCLC
Scott J. Antonia,A. Villegas,Davey B. Daniel,David Vicente,Shuji Murakami,Rina Hui,Takayasu Kurata,A. Chiappori,Ki Hyeong Lee,Maike de Wit,Byoung Cheol Cho,M. Bourhaba,Xavier Quantin,Takaaki Tokito,Tarek Mekhail,David Planchard,Young-Chul Kim,Christos S. Karapetis,Sandrine Hiret,Gyula Ostoros,Kaoru Kubota,Jhanelle E. Gray,Luis Paz-Ares,Javier de Castro Carpeño,Corinne Faivre-Finn,Martin Reck,Johan Vansteenkiste,David R. Spigel,Catherine Wadsworth,Giovanni Melillo,Maria Taboada,Phillip A. Dennis,Mustafa Ozguroglu +32 more
TL;DR: Durvalumab therapy resulted in significantly longer overall survival than placebo, and no new safety signals were identified.
Journal ArticleDOI
Predictive relevance of PD-L1 expression combined with CD8+ TIL density in stage III non-small cell lung cancer patients receiving concurrent chemoradiotherapy
Takaaki Tokito,Koichi Azuma,Akihiko Kawahara,Hidenobu Ishii,Kazuhiko Yamada,Norikazu Matsuo,Takashi Kinoshita,Naohisa Mizukami,Hirofumi Ono,Masayoshi Kage,Tomoaki Hoshino +10 more
TL;DR: It is proposed that PD-L1 expression in combination with CD8+ TIL density could be a useful predictive biomarker in patients with stage III NSCLC.
Journal ArticleDOI
Significance of programmed cell death-ligand 1 expression and its association with survival in patients with small cell lung cancer.
Hidenobu Ishii,Koichi Azuma,Akihiko Kawahara,Kazuhiko Yamada,Yohei Imamura,Takaaki Tokito,Takashi Kinoshita,Masayoshi Kage,Tomoaki Hoshino +8 more
TL;DR: In patients with SCLC, expression of PD-L1 is positively correlated with a LD stage, and is independently predictive of a favorable outcome, independently of other factors.
Journal ArticleDOI
Prognostic impact of cancer cachexia in patients with advanced non-small cell lung cancer
Madoka Kimura,Tateaki Naito,Hirotsugu Kenmotsu,Tetsuhiko Taira,Kazushige Wakuda,Takuya Oyakawa,Yasushi Hisamatsu,Takaaki Tokito,Hisao Imai,Hiroaki Akamatsu,Akira Ono,Kyoichi Kaira,Haruyasu Murakami,Masahiro Endo,Keita Mori,Toshiaki Takahashi,Nobuyuki Yamamoto +16 more
TL;DR: CC presence and decreased skeletal muscle mass are associated with poor prognosis in advanced NSCLC patients receiving chemotherapy.