T
Takanori Yasukochi
Researcher at University of Tsukuba
Publications - 8
Citations - 147
Takanori Yasukochi is an academic researcher from University of Tsukuba. The author has contributed to research in topics: Arthritis & Antibody. The author has an hindex of 6, co-authored 8 publications receiving 139 citations. Previous affiliations of Takanori Yasukochi include National Presto Industries & Novartis.
Papers
More filters
Journal ArticleDOI
Therapeutic effects of antibodies to tumor necrosis factor-α, interleukin-6 and cytotoxic T-lymphocyte antigen 4 immunoglobulin in mice with glucose-6-phosphate isomerase induced arthritis
Isao Matsumoto,Hua Zhang,Takanori Yasukochi,Keiichi Iwanami,Yoko Tanaka,Asuka Inoue,Daisuke Goto,Satoshi Ito,Akito Tsutsumi,Takayuki Sumida +9 more
TL;DR: TNF-α and IL-6 play an important role in GPI-induced arthritis, whereas IFN-γ appears to function as a regulator of arthritis.
Journal ArticleDOI
Overexpression of phosphorylated STAT-1α in the labial salivary glands of patients with Sjögren's syndrome
Ei Wakamatsu,Isao Matsumoto,Takanori Yasukochi,Yusuke Naito,Daisuke Goto,Mizuko Mamura,Satoshi Ito,Akito Tsutsumi,Takayuki Sumida +8 more
TL;DR: Evidence is found of the up-regulation of STAT-1alpha mRNA and protein in LSGs from SS patients, as well as the presence of pSTAT-1 alpha in ductal epithelium fromSS patients.
Journal ArticleDOI
Use of laser microdissection in the analysis of renal-infiltrating T cells in MRL/lpr mice
Yingge Wang,Satoshi Ito,Yusuke Chino,Keiichi Iwanami,Takanori Yasukochi,Daisuke Goto,Isao Matsumoto,Taichi Hayashi,Kazuhiko Uchida,Takayuki Sumida +9 more
TL;DR: The results of this study suggest that the pathogenesis of renal lesions in MRL/lpr mice is complex and not due simply to the Th1 and Th2 balance, and support the concept of different molecular mechanisms for glomerulonephritis and vasculitis in these mice.
Journal ArticleDOI
A functional variant of Fcγ receptor IIIA is associated with rheumatoid arthritis in individuals who are positive for anti-glucose-6-phosphate isomerase antibodies
Isao Matsumoto,Isao Matsumoto,Hua Zhang,Hua Zhang,Yoshifumi Muraki,Taichi Hayashi,Takanori Yasukochi,Takanori Yasukochi,Yuko Kori,Daisuke Goto,Satoshi Ito,Akito Tsutsumi,Takayuki Sumida +12 more
TL;DR: The association of FCGR3A-158V/F functional polymorphism with anti-GPI antibody positive status is reported, providing a molecular model of the genetic regulation of autoantibody-induced arthritis by allele-specific affinity of the FcγRs.
Journal ArticleDOI
Immunoglobulin G from anti-glucose-6-phosphate isomerase antibodies positive patient with rheumatoid arthritis induces synovitis in cynomolgus monkeys.
Takeshi Suzuki,Yoshifumi Muraki,Takanori Yasukochi,Takanori Yasukochi,Hua Zhang,Hua Zhang,Yuko Kori,Ei Wakamatsu,Taichi Hayashi,Daisuke Goto,Satoshi Ito,Akito Tsutsumi,Hiroshi Sumichika,Takayuki Sumida,Isao Matsumoto,Isao Matsumoto +15 more
TL;DR: The results suggest that IgG fraction from RA patients including anti-GPI Abs may play a crucial role in the generation of synovitis in monkeys, although the pathogenesis of anti- GPI Abs in RA patients is still uncertain.