Taichi Hayashi

TL;DR: New classification criteria for IIM have been endorsed by international rheumatology, dermatology, neurology and paediatric groups, and have been partially validated and generally perform better than existing criteria.

TL;DR: To develop and validate new classification criteria for adult and juvenile idiopathic inflammatory myopathies (IIM) and their major subgroups.

TL;DR: The new EULAR/ACR classification criteria provide a patient’s probability of having IIM for use in clinical and research settings and a classification tree for subclassification of patients with IIM is developed.

TL;DR: The expression level of IL‐17 was correlated closely with clinical parameters such as haematuria, blood urea nitrogen level, SLE Disease Activity Index scores in both glomersuli and interstitium, urine protein level in glomeruli and serum creatinine and Creatinine clearance levels in interst itium, which suggests that IL‐ 17 might play a critical role in SLE development.

TL;DR: The same STAT4 risk allele is associated with SLE in Caucasian and Japanese populations and the contribution of STAT4 for the genetic background of SLE may be greater in the Japanese population than in Americans of European descent.