T
Takao Endo
Researcher at Sapporo Medical University
Publications - 9
Citations - 1816
Takao Endo is an academic researcher from Sapporo Medical University. The author has contributed to research in topics: Regulation of gene expression & DNA methylation. The author has an hindex of 8, co-authored 9 publications receiving 1725 citations.
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Journal ArticleDOI
The expression of matrix metalloproteinase matrilysin indicates the degree of inflammation in ulcerative colitis
Keiki Matsuno,Yasushi Adachi,Hiroyuki Yamamoto,Akira Goto,Yoshiaki Arimura,Takao Endo,Fumio Itoh,Kohzoh Imai +7 more
TL;DR: Matrilysin expression could be an important marker of activity and could be used for the prediction of subsequent transformation in patients with ulcerative colitis.
Journal ArticleDOI
Interplay of insulin-like growth factor-II, insulin-like growth factor-I, insulin-like growth factor-I receptor, COX-2, and matrix metalloproteinase-7, play key roles in the early stage of colorectal carcinogenesis.
Katsuhiko Nosho,Hiroyuki Yamamoto,Hiroaki Taniguchi,Yasushi Adachi,Yukinari Yoshida,Yoshiaki Arimura,Takao Endo,Yuji Hinoda,Kohzoh Imai +8 more
TL;DR: IGF-II, in conjunction with IGF-IR, IGF-I, COX-2, and MMP-7, seems to play a key role in the early stage of colorectal carcinogenesis.
Journal ArticleDOI
Increased cyclooxygenase-2 expression in large flat colorectal tumors (laterally spreading tumors).
Kentaro Yamashita,Yoshiaki Arimura,Haruo Shimizu,Hiroaki Takahashi,Takao Endo,Kohzoh Imai,Hiro-o Yamano +6 more
TL;DR: Overexpression of COX-2 protein may play a crucial role in the tumorigenesis of colorectal LSTs and Chemoprevention, using nonsteroidal anti-inflammatory drugs (NSAIDs) or selective COx-2 inhibitors may be effective for treating this unique neoplasm, which sometimes defies endoscopic treatment.