T
Takehiko Sasazuki
Researcher at Kyushu University
Publications - 407
Citations - 25388
Takehiko Sasazuki is an academic researcher from Kyushu University. The author has contributed to research in topics: Human leukocyte antigen & Antigen. The author has an hindex of 78, co-authored 404 publications receiving 24042 citations. Previous affiliations of Takehiko Sasazuki include Onyx Pharmaceuticals & University of Toronto.
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Journal ArticleDOI
Nomenclature for factors of the HLA system, 2010.
Steven G.E. Marsh,E. D. Albert,Walter F. Bodmer,Ronald E. Bontrop,Bo Dupont,Henry A. Erlich,Marcelo Fernandez-Vina,Daniel E. Geraghty,Rhonda Holdsworth,Carolyn Katovich Hurley,M. Lau,Keun-Seok Lee,Bernard Mach,Martin Maiers,Wolfgang R. Mayr,Carlheinz Müller,Peter Parham,Effie W. Petersdorf,Takehiko Sasazuki,Jack L. Strominger,A. Svejgaard,Paul I. Terasaki,Jean-Marie Tiercy,John Trowsdale +23 more
TL;DR: This report documents the additions and revisions to the nomenclature of HLA specificities following the principles established in previous reports.
Journal Article
Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis.
Janusz Rak,Y. Mitsuhashi,L. Bayko,Jorge Filmus,Senji Shirasawa,Takehiko Sasazuki,Robert S. Kerbel +6 more
TL;DR: The results suggest that dominantly acting ras oncogenes may contribute to the growth of solid tumors in vivo not only by a direct effect on tumor cell proliferation but also indirectly, i.e., by facilitating tumor angiogenesis.
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Altered growth of human colon cancer cell lines disrupted at activated Ki-ras
TL;DR: The activated Ki-ras gene plays a key role in colorectal tumorigenesis through altered cell differentiation and cell growth.
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Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy
Akinori Kimura,Haruhito Harada,Jeong-Euy Park,Hirofumi Nishi,Manatsu Satoh,Megumi Takahashi,Shitoshi Hiroi,Taishi Sasaoka,Nobuhisa Ohbuchi,Takeyuki Nakamura,Takeshi Koyanagi,Tae-Hong Hwang,Jina Choo,Kyu-Sung Chung,Akira Hasegawa,Ryozo Nagai,Osamu Okazaki,Hiroshi Nakamura,Masunori Matsuzaki,Tsuguya Sakamoto,Hironori Toshima,Yoshinori Koga,Tsutomu Imaizumi,Takehiko Sasazuki +23 more
TL;DR: Family studies showed that an Arg145Gly mutation was linked to HCM and a Lys206Gln mutation had occurred de novo, thus strongly suggesting that cTnl is the seventh HCM gene, and systematically characterized the cardiac sarcomere genes.
Journal ArticleDOI
Effect of matching of class I HLA alleles on clinical outcome after transplantation of hematopoietic stem cells from an unrelated donor
Takehiko Sasazuki,Takeo Juji,Yasuo Morishima,Naoko Kinukawa,Hidehiko Kashiwabara,Hidetoshi Inoko,Takato Yoshida,Akinori Kimura,Tatsuya Akaza,Nobuhiro Kamikawaji,Yoshihisa Kodera,Fumimaro Takaku,Yoshiaki Nose,Takashi Ono,Takeo Sakamaki,Shunichi Kato,Yuichi Akiyama,Shinichiro Okamoto,Hiroo Dohy,Mine Harada,Shigetaka Asano +20 more
TL;DR: Genomic typing of class I HLA alleles adds substantially to the success of transplantation of hematopoietic stem cells from unrelated donors, even if the donors are serologically identical to their recipients with respect to HLA-A, B, and DR antigens.