T
Takehito Shukuya
Researcher at Juntendo University
Publications - 128
Citations - 3169
Takehito Shukuya is an academic researcher from Juntendo University. The author has contributed to research in topics: Lung cancer & Chemotherapy. The author has an hindex of 26, co-authored 104 publications receiving 2536 citations. Previous affiliations of Takehito Shukuya include Ohio State University.
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Journal ArticleDOI
Alectinib versus crizotinib in patients with ALK-positive non-small-cell lung cancer (J-ALEX): an open-label, randomised phase 3 trial
Toyoaki Hida,Hiroshi Nokihara,Masashi Kondo,Young Hak Kim,Koichi Azuma,Takashi Seto,Yuichi Takiguchi,Makoto Nishio,Hiroshige Yoshioka,Fumio Imamura,Katsuyuki Hotta,Satoshi Watanabe,Koichi Goto,Miyako Satouchi,Toshiyuki Kozuki,Takehito Shukuya,Kazuhiko Nakagawa,Tetsuya Mitsudomi,Nobuyuki Yamamoto,Takashi Asakawa,Ryoichi Asabe,Tomohiro Tanaka,Tomohide Tamura +22 more
TL;DR: These results provide the first head-to-head comparison of alectinib and crizotinib and have the potential to change the standard of care for the first-line treatment of ALK-positive non-small-cell lung cancer.
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Predictive Markers for the Efficacy of Anti–PD-1/PD-L1 Antibodies in Lung Cancer
TL;DR: There is an urgent need for effective predictive biomarkers to identify patients likely to benefit from anti-PD-1/PD-L1 antibodies in NSCLC and the existing data on predictive markers for the efficacy are reviewed.
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The risk of cytotoxic chemotherapy-related exacerbation of interstitial lung disease with lung cancer.
Hirotsugu Kenmotsu,Tateaki Naito,Madoka Kimura,Akira Ono,Takehito Shukuya,Yukiko Nakamura,Asuka Tsuya,Kyoichi Kaira,Haruyasu Murakami,Toshiaki Takahashi,Masahiro Endo,Nobuyuki Yamamoto +11 more
TL;DR: The results indicated that the incidence of exacerbation of ILD was significantly higher in patients with lung cancer with UIP pattern on CT findings than in those with non-UIP pattern.
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Prognostic Impact of Circulating Tumor Cells in Patients with Small Cell Lung Cancer
Tateaki Naito,Fumihiro Tanaka,Akira Ono,Kazue Yoneda,Toshiaki Takahashi,Haruyasu Murakami,Yukiko Nakamura,Asuka Tsuya,Hirotsugu Kenmotsu,Takehito Shukuya,Kyoichi Kaira,Yasuhiro Koh,Masahiro Endo,Seiki Hasegawa,Nobuyuki Yamamoto +14 more
TL;DR: CTCs were highly detectable in SCLC, and higher CTC levels were strongly associated with worse survival, and consistently favorable C TC levels were associated with favorable outcomes.
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Size-Based Isolation of Circulating Tumor Cells in Lung Cancer Patients Using a Microcavity Array System
Masahito Hosokawa,Hirotsugu Kenmotsu,Yasuhiro Koh,Tomoko Yoshino,Takayuki Yoshikawa,Tateaki Naito,Toshiaki Takahashi,Haruyasu Murakami,Yukiko Nakamura,Asuka Tsuya,Takehito Shukuya,Akira Ono,Hiroaki Akamatsu,Reiko Watanabe,Sachiyo Ono,Keita Mori,Hisashige Kanbara,Ken Yamaguchi,Tsuyoshi Tanaka,Tadashi Matsunaga,Nobuyuki Yamamoto +20 more
TL;DR: The MCA system has a potential to isolate significantly more CTCs and CTC clusters in advanced lung cancer patients compared to the CellSearch system, which employs the conventional EpCAM-based method.