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Yasuhiro Koh
Researcher at Wakayama Medical University
Publications - 109
Citations - 2956
Yasuhiro Koh is an academic researcher from Wakayama Medical University. The author has contributed to research in topics: Lung cancer & Circulating tumor cell. The author has an hindex of 28, co-authored 109 publications receiving 2419 citations.
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Journal ArticleDOI
Correlation between immune-related adverse events and efficacy in non-small cell lung cancer treated with nivolumab.
Koichi Sato,Hiroaki Akamatsu,Eriko Murakami,Seigo Sasaki,Kuninobu Kanai,Atsushi Hayata,Nahomi Tokudome,Keiichiro Akamatsu,Yasuhiro Koh,Hiroki Ueda,Masanori Nakanishi,Nobuyuki Yamamoto +11 more
TL;DR: There was a correlation between irAE and efficacy in NSCLC patients treated with nivolumab, and patients with irAEs had significantly higher ORRs compared with no-irAE patients.
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Ultra-sensitive detection of the pretreatment EGFR T790M mutation in non-small-cell lung cancer patients with an EGFR-activating mutation using droplet digital PCR
Masaru Watanabe,Tomoya Kawaguchi,Shun-ichi Isa,Masahiko Ando,Akihiro Tamiya,Akihito Kubo,Hideo Saka,Sadanori Takeo,Hirofumi Adachi,Tsutomu Tagawa,Seiichi Kakegawa,Motohiro Yamashita,Kazuhiko Kataoka,Yukito Ichinose,Yukiyasu Takeuchi,Kazuhiro Sakamoto,Akihide Matsumura,Yasuhiro Koh +17 more
TL;DR: The ultra-sensitive ddPCR assay revealed that pretreatment T790M was found in the majority of NSCLC patients with EGFR-activating mutations, which is a major concern in non–small cell lung cancer treatment.
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Prognostic Impact of Circulating Tumor Cells in Patients with Small Cell Lung Cancer
Tateaki Naito,Fumihiro Tanaka,Akira Ono,Kazue Yoneda,Toshiaki Takahashi,Haruyasu Murakami,Yukiko Nakamura,Asuka Tsuya,Hirotsugu Kenmotsu,Takehito Shukuya,Kyoichi Kaira,Yasuhiro Koh,Masahiro Endo,Seiki Hasegawa,Nobuyuki Yamamoto +14 more
TL;DR: CTCs were highly detectable in SCLC, and higher CTC levels were strongly associated with worse survival, and consistently favorable C TC levels were associated with favorable outcomes.
Journal ArticleDOI
Size-Based Isolation of Circulating Tumor Cells in Lung Cancer Patients Using a Microcavity Array System
Masahito Hosokawa,Hirotsugu Kenmotsu,Yasuhiro Koh,Tomoko Yoshino,Takayuki Yoshikawa,Tateaki Naito,Toshiaki Takahashi,Haruyasu Murakami,Yukiko Nakamura,Asuka Tsuya,Takehito Shukuya,Akira Ono,Hiroaki Akamatsu,Reiko Watanabe,Sachiyo Ono,Keita Mori,Hisashige Kanbara,Ken Yamaguchi,Tsuyoshi Tanaka,Tadashi Matsunaga,Nobuyuki Yamamoto +20 more
TL;DR: The MCA system has a potential to isolate significantly more CTCs and CTC clusters in advanced lung cancer patients compared to the CellSearch system, which employs the conventional EpCAM-based method.
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Biologic Correlation of 2-[18F]-Fluoro-2-Deoxy-D-Glucose Uptake on Positron Emission Tomography in Thymic Epithelial Tumors
Kyoichi Kaira,Masahiro Endo,Masato Abe,Kazuo Nakagawa,Yasuhisa Ohde,Takehiro Okumura,Toshiaki Takahashi,Haruyasu Murakami,A. Tsuya,Yukiko Nakamura,Tateaki Naito,Isamu Hayashi,Masakuni Serizawa,Yasuhiro Koh,Hirofumi Hanaoka,Hideyuki Tominaga,Noboru Oriuchi,Haruhiko Kondo,Takashi Nakajima,Nobuyuki Yamamoto +19 more
TL;DR: In vitro study demonstrated that upregulation of GLUT1 and HIF-1alpha was closely associated with [(18)F]FDG uptake into thymic tumor cell, whereas this relationship was not observed in GLUT3 and bcl-2.