Takeo Suzuki

TL;DR: A large number of nuclear factors involved in the biogenesis and function of mt tRNAs have been identified and characterized, including processing endonucleases, tRNA-modifying enzymes, and aminoacyl-tRNA synthetases, indicating the functional importance of mttRNAs for mitochondrial activity.

TL;DR: It is shown that piRNAs in Drosophila are 2'-O-methylated at their 3' ends, and Pimet mediates piRNA 2'- O-methylation in Dosophila.

TL;DR: In livers from GLD-2-null mice, the steady-state level of the mature form of miR-122 was specifically lower than in heterozygous mice, whereas no reduction of pre-miR- 122 was observed, demonstrating that 3'-terminal adenylation by GLd-2 is required for the selective stabilization of mi R-122 in the liver.

TL;DR: This is the first reported evidence that taurine is a constituent of biological macromolecules, unveiling the prospect of obtaining new insights into the functions and subcellular localization of this abundant amino acid.

TL;DR: In mammalian mitochondria, 22 species of tRNAs encoded in mitochondrial DNA play crucial roles in the translation of 13 essential subunits of the respiratory chain complexes involved in oxidative phosphorylation, and comprehensively determined the post-transcriptional modifications in each tRNA by mass spectrometry.