Showing papers by "Takeru Higuchi published in 1961"

TL;DR: An equation relating the rate of release of solid drugs suspended in ointment bases into perfect sinks is derived and the final expression is found to be surprisingly simple and convenient.

TL;DR: The data show that introduction of —OH into the first group, particularly ortho to a carboxylate grouping, produced marked enhancement in binding and the relative magnitude of the constants suggest that neither the squeezing out force nor hydrogen bonding is significantly responsible for the observed effects.

TL;DR: Of all the salts studied, sodium pamoate exhibited the strongest tendency with a stability constant of 160 L./mole for prednisolone, and the rather generalized binding effects observed earlier were again observed.

TL;DR: Although the study reported is restricted to mechanical measurements on isolated callus strips, it is suggested that the information reflects, in some measure, in vivo behavior of related keratin structures such as the stratum corneum.

TL;DR: In this article, three equations have been presented for the linear extrapolation of photometric indicator titration data to yield the end-point and the equilibrium constant for the titration reaction BHA + I ∡ IHA + B, which controls the color change of the indicator I in titration of the base B with the acid HA.

TL;DR: Theoretical and experimental analysis of volume-temperature curves of thymol containing naphthalene as the impurity shows that dilatometry can be applied to purity determinations of organic substances.