T
Takuya Sasaki
Researcher at University of Tokyo
Publications - 273
Citations - 18649
Takuya Sasaki is an academic researcher from University of Tokyo. The author has contributed to research in topics: Rab & GTP'. The author has an hindex of 72, co-authored 246 publications receiving 17515 citations. Previous affiliations of Takuya Sasaki include Tohoku University & Saitama University.
Papers
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Journal ArticleDOI
Small GTP-Binding Proteins
TL;DR: In this review, functions of small G proteins and their modes of activation and action are described.
Journal ArticleDOI
Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP
TL;DR: It is demonstrated that before it can induce filopodium formation, Cdc42 must bind a WASP-related protein, N-WASP, that is richest in neural tissues but is expressed ubiquitously.
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Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway.
M Hirao,N Sato,Tohru Kondo,Shigenobu Yonemura,M Monden,Takuya Sasaki,Yoshimi Takai,Shoichiro Tsukita +7 more
TL;DR: Findings indicate that Rho regulates the CD44/ERM complex formation in vivo and that the phosphatidylinositol turnover may be involved in this regulation mechanism.
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Regulation of Cell–Cell Adhesion by Rac and Rho Small G Proteins in MDCK Cells
TL;DR: The results suggest that the Rho subfamily is necessary for the formation of both the cadherin-based cell– cell adhesion and the tight junction, but not essential for the Rac subfamily-regulated, cadherIn-basedCell–cell adhesion.
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Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction
Ken-ichi Hirata,Akira Kikuchi,Takuya Sasaki,Shinya Kuroda,K Kaibuchi,Yoshiharu Matsuura,H. Seki,K. Saida,Yoshimi Takai +8 more
TL;DR: Results indicate that rhoA p21 is involved in the GTP gamma S-enhanced Ca2+ sensitivity of the smooth muscle contraction.