T
Tamara Shiner
Researcher at Tel Aviv Sourasky Medical Center
Publications - 33
Citations - 1302
Tamara Shiner is an academic researcher from Tel Aviv Sourasky Medical Center. The author has contributed to research in topics: Dementia with Lewy bodies & Parkinson's disease. The author has an hindex of 13, co-authored 27 publications receiving 1053 citations. Previous affiliations of Tamara Shiner include Tel Aviv University & Wellcome Trust Centre for Neuroimaging.
Papers
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Journal ArticleDOI
Dopamine, affordance and active inference.
Karl J. Friston,Tamara Shiner,Thomas H. B. FitzGerald,Joseph M. Galea,Rick A. Adams,Harriet R. Brown,Raymond J. Dolan,Rosalyn J. Moran,Klaas E. Stephan,Sven Bestmann +9 more
TL;DR: This paper focuses on the consequences of changing tonic levels of dopamine firing using simulations of cued sequential movements and uses these simulations to demonstrate how a single functional role for dopamine at the synaptic level can manifest in different ways at the behavioural level.
Journal ArticleDOI
Dopamine, Time, and Impulsivity in Humans
TL;DR: It is demonstrated that pharmacologically enhancing dopamine activity increases impulsivity by enhancing the diminutive influence of increasing delay on reward value and its corresponding neural representation in the striatum, which leads to a state of excessive discounting of temporally distant, relative to sooner, rewards.
Journal ArticleDOI
Dopamine and performance in a reinforcement learning task: evidence from Parkinson's disease.
Tamara Shiner,Ben Seymour,Klaus Wunderlich,Ciaran Scott Hill,Kailash P. Bhatia,Peter Dayan,Raymond J. Dolan +6 more
TL;DR: It is found that dopamine modulation of nucleus accumbens and ventromedial prefrontal cortex exerts a specific effect on choice behaviour distinct from pure learning, and that dopamine plays a key role in performance that may be distinct from its role in learning.
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Dopamine Enhances Expectation of Pleasure in Humans
TL;DR: It is shown that administration of a drug that enhances dopaminergic function during the imaginative construction of positive future life events subsequently enhances estimates of the hedonic pleasure to be derived from these same events.
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Parkinson's disease phenotype is influenced by the severity of the mutations in the GBA gene.
Avner Thaler,Noa Bregman,Tanya Gurevich,Tamara Shiner,Yonatan Dror,Ofir Zmira,Ziv Gan-Or,Anat Bar-Shira,Mali Gana-Weisz,Avi Orr-Urtreger,Nir Giladi,Anat Mirelman +11 more
TL;DR: Motor, cognitive, olfactory and psychiatric symptoms are more severe in sGBA and GD-PD compared to mGBAand iPD, reinforcing the notion that the severity of the PD phenotype is related to the severityof the mutation in the GBA gene.