T
Tamás F. Freund
Researcher at Hungarian Academy of Sciences
Publications - 237
Citations - 33521
Tamás F. Freund is an academic researcher from Hungarian Academy of Sciences. The author has contributed to research in topics: Hippocampal formation & Parvalbumin. The author has an hindex of 96, co-authored 235 publications receiving 31361 citations. Previous affiliations of Tamás F. Freund include Pázmány Péter Catholic University & University of Szeged.
Papers
More filters
Journal ArticleDOI
Mossy cells of the rat dentate gyrus are immunoreactive for calcitonin gene-related peptide (cgrp)
TL;DR: Direct evidence is provided that CGRP is present in mossy cells of the dentate gyrus and to a lesser degree in CA3c pyramidal Cells of the ventral hippocampus and may release the neuropeptide in conjunction with their ‘classical’ neurotransmitter, glutamate.
Journal ArticleDOI
Changes in excitatory and inhibitory circuits of the rat hippocampus 12-14 months after complete forebrain ischemia.
TL;DR: The loss of inhibitory interneurons at the first two stages of the trisynaptic loop coupled with a well-preserved excitatory connectivity among the subfields suggests that hyperexcitability in the surviving dentate gyrus and CA3 may persist even a year after the ischemic impact.
Journal ArticleDOI
Evidence of intraneuronal Aβ accumulation preceding tau pathology in the entorhinal cortex.
Lindsay A. Welikovitch,Sonia Do Carmo,Zsófia Maglóczky,Péter Szocsics,János Lőke,Tamás F. Freund,A. Claudio Cuello +6 more
TL;DR: It is shown for the first time in post-mortem human brain that Aβ oligomers do in fact accumulate intraneuronally, before the formation of extracellular plaques, and this findings indicate that the lifelong accrual of intraneuronal Aβ may be a potential trigger for downstream AD-related pathogenic events in early disease stages.
Journal ArticleDOI
Recurrent axon collaterals of corticothalamic projection neurons in rat primary somatosensory cortex contribute to excitatory and inhibitory feedback-loops.
TL;DR: Most synapses of corticothalamic projection neurons found in layers IV and V terminate on spines and shafts of GABA-negative dendrites, which suggests that such recurrent collaterals are involved in both excitatory and inhibitory feedback mechanisms.
Journal ArticleDOI
Enkephalin‐containing interneurons are specialized to innervate other interneurons in the hippocampal CA1 region of the rat and guinea‐pig
José Miguel Blasco-Ibáñez,José Miguel Blasco-Ibáñez,Francisco José Martínez-Guijarro,Tamás F. Freund +3 more
TL;DR: The morphological characteristics of met‐enkephalin‐immunoreactive cells in the CA1 region of the rat and guinea‐pig hippocampus are analysed, their coexistence with other neuronal markers and their target selectivity at the light and electron microscopic levels.