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Tamás F. Freund

Researcher at Hungarian Academy of Sciences

Publications -  237
Citations -  33521

Tamás F. Freund is an academic researcher from Hungarian Academy of Sciences. The author has contributed to research in topics: Hippocampal formation & Parvalbumin. The author has an hindex of 96, co-authored 235 publications receiving 31361 citations. Previous affiliations of Tamás F. Freund include Pázmány Péter Catholic University & University of Szeged.

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CB1 cannabinoid receptors mediate anxiolytic effects: convergent genetic and pharmacological evidence with CB1-specific agents.

József Haller, +3 more
- 01 Jul 2004 - 
TL;DR: The studies on the behavioural effects of the cannabinoid antagonist SR-141716A and theCB1 antagonist AM-251 show that the CB1 and the novel cannabinoid receptor mediate anxiolytic and anxiogenic effects, respectively, which suggests that agonists of the former, or antagonists of the latter, are promising new compounds in the pharmacotherapy of anxiety.
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Fast Synaptic Subcortical Control of Hippocampal Circuits

Viktor Sebestyén Varga, +10 more
- 16 Oct 2009 - 
TL;DR: A form of subcortical control of cortical information processing whereby strong, spatiotemporally precise excitatory input from midbrain serotonergic neurons produces a robust activation of hippocampal interneurons is described.
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The KCl cotransporter, KCC2, is highly expressed in the vicinity of excitatory synapses in the rat hippocampus

Attila I. Gulyás, +4 more
- 01 Jun 2001 - 
TL;DR: KCC2 located in the same microenvironment may provide a Cl– extrusion mechanism to deal with both ion and water homeostasis in addition to its role in setting the driving force of Cl– currents involved in fast postsynaptic inhibition.
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Precision and variability in postsynaptic target selection of inhibitory cells in the hippocampal CA3 region

Attila I. Gulyás, +3 more
- 01 Dec 1993 - 
TL;DR: The results show that a restricted set of inhibitory cells, with somata within or close to CA3 stratum pyramldale, possess variable patterns of axonal arborization.
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Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus.

Judit K. Makara, +11 more
- 01 Sep 2005 - 
TL;DR: Two previously unknown inhibitors of monoacylglycerol lipase, a presynaptic enzyme that hydrolyzes 2-AG, increase 2- AG levels and enhance retrograde signaling from pyramidal neurons to GABAergic terminals in the hippocampus are shown.