Tamás F. Freund

TL;DR: It is shown that the activity-dependent, retrograde inhibition of GABA release by endogenous cannabinoids is persistently enhanced in the rat hippocampus following a single episode of experimental prolonged febrile seizures during early postnatal development.

TL;DR: In this paper, the authors used in vivo juxtacellular recording and filling in the medial septum followed by immunocytochemical identification of the recorded cells containing parvalbumin to determine their firing pattern, phase relationship with hippocampal theta, morphology, and to reveal their involvement in the generation of hippocampal hippocampus theta activity.

TL;DR: The present data are consistent with a role of endocannabinoids in the control of GABA, but not glutamate, release in the basal ganglia via presynaptic CB1 receptors, but also call the attention to possible non-CB1-mediated effects of widely used cannabinoid ligands on action potential generation.

TL;DR: The correlation of these features with the content of neurochemical markers strongly suggests that vasoactive intestinal polypeptide-immunoreactive interneurons are specialized for distinct inhibitory functions in the hippocampal network.

TL;DR: Electron microscopic analysis provided evidence that the axon terminals of CA1‐HS cells form symmetrical synapses selectively on GABAergic interneurons, both locally and in the CA3 region, ideally suited to synchronize neuronal activity along the septo‐hippocampal axis.