T
Tammy T. Hshieh
Researcher at Brigham and Women's Hospital
Publications - 70
Citations - 3435
Tammy T. Hshieh is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Delirium & Medicine. The author has an hindex of 20, co-authored 60 publications receiving 2175 citations. Previous affiliations of Tammy T. Hshieh include Beth Israel Deaconess Medical Center & Harvard University.
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Journal ArticleDOI
Delirium in Older Persons: Advances in Diagnosis and Treatment.
TL;DR: Avoiding use of antipsychotics and other sedating medications for treatment of severe agitation that poses risk to patient or staff safety or threatens interruption of essential medical therapies is recommended.
Journal ArticleDOI
Effectiveness of Multicomponent Nonpharmacological Delirium Interventions: A Meta-analysis
Tammy T. Hshieh,Jirong Yue,Esther S. Oh,Margaret R. Puelle,Sarah L. Dowal,Thomas G. Travison,Sharon K. Inouye +6 more
TL;DR: A meta-analysis supports the use of multicomponent nonpharmacological delirium prevention interventions to advance acute care for older persons, with a trend toward decreasing length of stay and avoiding institutionalization.
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The Low Density Lipoprotein Receptor-related Protein (LRP) Is a Novel β-Secretase (BACE1) Substrate
Christine A F Von Arnim,Ayae Kinoshita,Ithan D. Peltan,Michelle M. Tangredi,Lauren Herl,Bonny M. Lee,Robert Spoelgen,Tammy T. Hshieh,Sripriya Ranganathan,Frances D. Battey,Chun Xiang Liu,Brian J. Bacskai,Sanja Sever,Michael C. Irizarry,Dudley K. Strickland,Bradley T. Hyman +15 more
TL;DR: In this paper, a new fluorescence resonance energy transfer (FRET)-based assay of protein proximity, fluorescence lifetime imaging (FLIM), and co-immunoprecipitation was demonstrated that the light chain of LRP interacts with BACE on the cell surface in association with lipid rafts.
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Hospital Elder Life Program: Systematic Review and Meta-analysis of Effectiveness
TL;DR: The systematic review revealed that programs were generally successful in adhering to or appropriately adapting HELP and in finding the volunteer role to be valuable, with a trend toward decreasing length of stay and preventing institutionalization.
Journal ArticleDOI
Delirium in Older Patients With COVID-19 Presenting to the Emergency Department.
Maura Kennedy,Benjamin K. I. Helfand,Benjamin K. I. Helfand,Ray Yun Gou,Sarah L. Gartaganis,Margaret Webb,J. Michelle Moccia,Stacey N. Bruursema,Belinda Dokic,Brigid McCulloch,Hope Ring,Justin D. Margolin,Ellen Zhang,Robert S. Anderson,Rhonda L. Babine,Tammy T. Hshieh,Ambrose H. Wong,R. Andrew Taylor,Kathleen Davenport,Brittni Teresi,Tamara G. Fong,Tamara G. Fong,Sharon K. Inouye,Sharon K. Inouye +23 more
TL;DR: It is suggested that older adults with COVID-19 commonly present to the emergency department (ED) with delirium and thatDelirium should be considered an important presenting symptom of CO VID-19.