T
Tao Huang
Researcher at Chinese Academy of Sciences
Publications - 325
Citations - 12593
Tao Huang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 41, co-authored 248 publications receiving 10196 citations. Previous affiliations of Tao Huang include CAS-MPG Partner Institute for Computational Biology & Shanghai Mental Health Center.
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Applications of Bioinformatics and Systems Biology in Precision Medicine and Immunooncology.
TL;DR: In this special issue, the received papers could be generally divided into 3 categories including computational models in identifying key biomarkers, pathways, and network modules associated with cancers and other diseases, and validations of the mechanisms of key biomarker and their applications in tumor diagnosis and treatment, and other studies in predicting tumor evolution, drug-disease association, disease sequence alignment, and so on.
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Sleep and Late-Onset Alzheimer’s Disease: Shared Genetic Risk Factors, Drug Targets, Molecular Mechanisms, and Causal Effects
TL;DR: Findings provide strong evidence of shared genetics and causation between AD and sleep abnormalities and advance the understanding of the genetic overlap between them.
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Integrative Analysis of Bulk and Single-Cell RNA Sequencing Data Reveals Cell Types Involved in Heart Failure
Xin Shi,Li Zhang,Yi Li,Jieyuan Xue,Feng Liang,Han Ni,Xia Wang,Zhaohua Cai,Linghong Shen,Tao Huang,Ben-Xiang He +10 more
TL;DR: These findings identified features of the landscape of previously underestimated cellular, transcriptomic heterogeneity between ICM and DCM, and suggested the EC and fibroblast could be activated in response to HF.
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New Computational Tool Based on Machine-learning Algorithms for the Identification of Rhinovirus Infection-Related Genes.
TL;DR: A novel approach that relies on machine-learning algorithms and identified two genes OTOF and SOCS1 suggests the crucial roles of these two genes in rhinovirus infection and the robustness of the computational tool in dissecting pathogenic mechanisms.
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MiR-26b regulates cartilage differentiation of bone marrow mesenchymal stem cells in rats through the Wnt/β-catenin signaling pathway.
TL;DR: MiR-26b plays an inhibitory role in the in vitro cartilage differentiation of rat MSCs by inhibiting Wnt expression and providing references for the clinical treatment of orthopedic diseases, such as osteoarthritis.