Tao Huang

TL;DR: In this paper, the authors identified specific regulatory factors and a series of rules that contribute to the activation and stimulation of airway smooth muscles by IL-13, IL-17, or the combination of both interleukins on the epigenetic and/or transcriptional levels.

TL;DR: This study analyzed the gene expression profiles of CD4+ T cells from HIV-1-resistant individuals and HIV-susceptible individuals to identify discriminative HIV- 1 resistance genes and identified 29 infection information exchanger genes that are located on the shortest paths between virus-targeted proteins and are important for the coordination of virus infection.

TL;DR: A novel sequence-based method for identifying the two main types of hydroxylation sites – hydroxyproline and hydroxylysine was developed and suggested that physicochemical properties and biochemical properties and evolution information of amino acids contribute much to the identification of the protein hydroxyation sites, while structural disorder had little relation to protein hydoxylation.

TL;DR: A novel method to discriminate ubiquitinated and acetylated lysine residues with feature selection and analysis, and supported previous findings that different motifs were employed by acetylation and ubiquitination.

TL;DR: This work developed a novel strategy to study inter-tissue interaction by removing effects of genetic regulation of gene expression (genetic decorrelation) and derived modules of genes important in inter-Tissue interactions that are likely driven by biological signal exchange instead of their common genetic basis.