T
Tao Huang
Researcher at Chinese Academy of Sciences
Publications - 325
Citations - 12593
Tao Huang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 41, co-authored 248 publications receiving 10196 citations. Previous affiliations of Tao Huang include CAS-MPG Partner Institute for Computational Biology & Shanghai Mental Health Center.
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Identification of Colorectal Cancer Related Genes with mRMR and Shortest Path in Protein-Protein Interaction Network
TL;DR: This study developed a computational method to identify colorectal cancer-related genes based on the gene expression profiles, and the shortest path analysis of functional protein association networks, which indicated that the method may become a useful tool, or at least plays a complementary role to the existing method.
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Predicting Functions of Proteins in Mouse Based on Weighted Protein-Protein Interaction Network and Protein Hybrid Properties
TL;DR: Results indicate that the new approach by hybridizing the PPI information and the biochemical/physicochemical features of protein sequences is quite promising that may open a new avenue or direction for addressing the difficult and complicated problem.
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Analysis and prediction of the metabolic stability of proteins based on their sequential features, subcellular locations and interaction networks.
Tao Huang,Xiao-He Shi,Ping Wang,Zhisong He,Kai-Yan Feng,Le-Le Hu,Xiangyin Kong,Yixue Li,Yu-Dong Cai,Yu-Dong Cai,Kuo-Chen Chou +10 more
TL;DR: There was an intriguing correlation between the predicted metabolic stability of some proteins and the real half-life of the drugs designed to target them and these findings might provide useful insights for designing protein-stability-relevant drugs.
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Prediction of lysine ubiquitination with mRMR feature selection and analysis
TL;DR: A sequence-based predictor of ubiquitination site prediction was developed based on nearest neighbor algorithm using the maximum relevance and minimum redundancy principle to identify the key features and the incremental feature selection procedure to optimize the prediction engine.
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Genetic differences among ethnic groups
Tao Huang,Yang Shu,Yu-Dong Cai +2 more
TL;DR: In-depth functional analysis of these SNPs and their nearby genes revealed the genetic bases of skin and eye color differences among populations.